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Growing and Pruning Based Deep Neural Networks Modeling for Effective Parkinson’s Disease Diagnosis

Kemal Akyol1, *

1 Kastamonu University, Kuzeykent Yerleşkesi, Kastamonu, 37100, Turkey.
* Corresponding Author: Kemal Akyol. Email:

(This article belongs to this Special Issue: Data Science and Modeling in Biology, Health, and Medicine)

Computer Modeling in Engineering & Sciences 2020, 122(2), 619-632.


Parkinson’s disease is a serious disease that causes death. Recently, a new dataset has been introduced on this disease. The aim of this study is to improve the predictive performance of the model designed for Parkinson’s disease diagnosis. By and large, original DNN models were designed by using specific or random number of neurons and layers. This study analyzed the effects of parameters, i.e., neuron number and activation function on the model performance based on growing and pruning approach. In other words, this study addressed the optimum hidden layer and neuron numbers and ideal activation and optimization functions in order to find out the best Deep Neural Networks model. In this context of this study, several models were designed and evaluated. The overall results revealed that the Deep Neural Networks were significantly successful with 99.34% accuracy value on test data. Also, it presents the highest prediction performance reported so far. Therefore, this study presents a model promising with respect to more accurate Parkinson’s disease diagnosis.


Cite This Article

Akyol, K. (2020). Growing and Pruning Based Deep Neural Networks Modeling for Effective Parkinson’s Disease Diagnosis. CMES-Computer Modeling in Engineering & Sciences, 122(2), 619–632.

This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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