Open Access

ARTICLE

Mitral valve prolapse and Marfan syndrome

Amitabh Thacoor

Department of Cardiac Surgery, Leeds General Infirmary, Great George Street, Leeds, United KIngdom

* Corresponding Author: Amitabh Thacoor, Department of Plastic and Reconstructive Surgery, Royal Free Hospital, Pond Street, London, NW32QG, UK. Email:

Congenital Heart Disease 2017, 12(4), 430-434. https://doi.org/10.1111/chd.12467

Abstract

Marfan syndrome is a multisystemic genetic condition affecting connective tissue. It carries a reduced life expectancy, largely dependent on cardiovascular complications. More common cardiac manifestations such as aortic dissection and aortic valve incompetence have been widely documented in the literature. Mitral valve prolapse (MVP), however, has remained poorly documented. This article aims at exploring the existing literature on the pathophysiology and diagnosis of MVP in patients with Marfan syndrome, defining its current management and outlining the future developments surrounding it.

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