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REVIEW

State of the art review: Chemotherapy-induced cardiotoxicity in children

Robert W. Loar, Cory V. Noel, Hari Tunuguntla, John L. Colquitt, Ricardo H. Pignatelli

Pediatric Cardiology, Texas Children’s Hospital/Baylor College of Medicine, Houston, Texas, USA

* Corresponding Author: Robert W. Loar, MD, Texas Children’s Hospital/Baylor College of Medicine, 6621 Fannin Street, MC 19345-C, Houston, TX 77030, USA. Email: email

Congenital Heart Disease 2018, 13(1), 5-15. https://doi.org/10.1111/chd.12564

Abstract

Chemotherapy-induced cardiotoxicity in adults and children is a topic with a growing interest in the cardiology literature. The ability to detect cardiac dysfunction in a timely manner is essential in order to begin adequate treatment and prevent further deterioration. This article aims to provide a review on the myocardial injury process, chemotherapeutic agents that lead to cardiotoxicity, the definition of cardiotoxicity, and the methods of timely detection and treatment.

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Cite This Article

Loar, R. W., Noel, C. V., Tunuguntla, H., Colquitt, J. L., Pignatelli, R. H. (2018). State of the art review: Chemotherapy-induced cardiotoxicity in children. Congenital Heart Disease, 13(1), 5–15.



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