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Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood

Charlotte A. Houck1,2, Reinder Evertz3, Christophe P. Teuwen1, Jolien W. Roos‐Hesselink1, Janneke A. E. Kammeraad4, Anthonie L. Duijnhouwer3, Natasja M. S. de Groot3, Ad J. J. C. Bogers2

1 Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands
2 Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands 3 Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands
4 Department of Pediatric Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands

* Corresponding Author: Ad J. J. C. Bogers, MD, PhD, Department of Cardiothoracic Surgery, Erasmus University Medical Center, RG‐619, Dr. Molewaterplein 40, Rotterdam 3015 GD, The Netherlands. Email: email

Congenital Heart Disease 2019, 14(2), 280-287. https://doi.org/10.1111/chd.12724

Abstract

Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD.
Study design: In this retrospective multicenter study, 74 patients (68% female) with a cAVSD repaired in childhood were included. Patients’ medical files were evaluated for occurrence of SND, atrioventricular conduction block (AVB), atrial and ventricular tachyarrhythmias.
Results: Median age at repair was 6 months (interquartile range 3‐10) and median age at last follow‐up was 24 years (interquartile range 21‐28). SND occurred after a me‐ dian of 17 years (interquartile range 11‐19) after repair in 23% of patients, requiring pacemaker implantation in two patients (12%). Regular supraventricular tachycardia was observed in three patients (4%). Atrial fibrillation and ventricular tachyarrhyth‐ mias were not observed. Twenty‐seven patients (36%) had first‐degree AVB, which was self‐limiting in 16 (59%) and persistent in 10 (37%) patients. One patient devel‐ oped third‐degree AVB 7 days after left atrioventricular valve replacement. Spontaneous type II second‐degree AVB occurred in a 28‐year‐old patient. Both pa‐ tients underwent pacemaker implantation.
Conclusions: Clinically significant dysrhythmias were uncommon in young adult pa‐ tients after cAVSD repair. However, three patients required pacemaker implantation for either progression of SND or spontaneous type II second‐degree AVB. Longer follow‐up should point out whether dysrhythmias will progress or become more prevalent with increasing age.

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APA Style
Houck, C.A., Evertz, R., Teuwen, C.P., Roos‐Hesselink, J.W., Kammeraad, J.A.E. et al. (2019). Dysrhythmias in patients with a complete atrioventricular septal defect: from surgery to early adulthood. Congenital Heart Disease, 14(2), 280-287. https://doi.org/10.1111/chd.12724
Vancouver Style
Houck CA, Evertz R, Teuwen CP, Roos‐Hesselink JW, Kammeraad JAE, Duijnhouwer AL, et al. Dysrhythmias in patients with a complete atrioventricular septal defect: from surgery to early adulthood. Congeni Heart Dis. 2019;14(2):280-287 https://doi.org/10.1111/chd.12724
IEEE Style
C.A. Houck et al., "Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood," Congeni. Heart Dis., vol. 14, no. 2, pp. 280-287. 2019. https://doi.org/10.1111/chd.12724



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