Open Access

ARTICLE

Hemodynamic Profile Based on Right Heart Catheterization in Adult Acyanotic Congenital Heart Disease with Pulmonary Hypertension

Dina Anggraini¹, Kurnia Wahyudi², Melawati Hasan³, Sri Endah Rahayuningsih^4,*, Charlotte Johanna Cool³

1 Faculty of Medicine, Padjadjaran University, Sumedang, 45363, Indonesia
2 Department of Public Health, Faculty of Medicine, Padjadjaran University, Bandung, 40161, Indonesia
3 Department of Cardiology, Dr.Hasan Sadikin General Hospital, Bandung, 40161, Indonesia
4 Department of Pediatrics, Dr. Hasan Sadikin General Hospital, Bandung, 40161, Indonesia

* Corresponding Author: Sri Endah Rahayuningsih. Email:

Congenital Heart Disease 2025, 20(2), 133-141. https://doi.org/10.32604/chd.2025.064164

Received 07 February 2025; Accepted 10 April 2025; Issue published 30 April 2025

Abstract

Background: Congenital heart disease (CHD) occurs in 9 out of 100 births and is the leading cause of birth defects, with acyanotic CHD being more common. The incidence of adult CHD is rising faster than pediatric CHD. Pulmonary hypertension is the most common complication in untreated CHD patients. Methods: This study is retrospective descriptive research based on medical record data and the results of right heart catheterization examinations in adult acyanotic CHD aged ≥18 years and free from other organ disorders. Results: A total of 103 patients met the inclusion criteria, the majority were young adults and predominantly female. The median height of 155.0 cm (IQR: 150.0–160.0), the mean weight was 49.6 kg ± 10.7 kg, and BSA of 1.4 m² ± 0.1 m². Most patients had a normal BMI status and were classified as WHO-FC II. Hemodynamic findings included a median PARI of 13.5 WU/m² (IQR: 4.5–29.6), RAP 7.0 mmHg (IQR: 5.0–11.0), mPAP 56.0 mmHg ± 23.5 mmHg, LVEDP 9.5 mmHg ± 3.9 mmHg, PVR 12.6 WU ± 11.0 WU, PVR/SVR 0.5 WU ± 0.4 WU, pulmonary artery saturation 74.0% ± 12.1%, aortic saturation 88.1% ± 7.8%, mixed venous saturation 59.0% ± 10.1%. Conclusions: This study provides comprehensive data on the demographic characteristics and hemodynamic parameters of patients with CHD and pulmonary hypertension. As a hospital-based registry, this study offers valuable insights into the clinical profile of adult CHD patients at Dr. Hasan Sadikin General Hospital, Bandung.

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