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Prediction of Parkinson’s Disease Using Improved Radial Basis Function Neural Network

Rajalakshmi Shenbaga Moorthy1,*, P. Pabitha2

1 St. Joseph’s Institute of Technology, Chennai, 600119, India
2 Madras Institute of Technology, Chennai, 600044, India

* Corresponding Author: Rajalakshmi Shenbaga Moorthy. Email:

Computers, Materials & Continua 2021, 68(3), 3101-3119.


Parkinson’s disease is a neurogenerative disorder and it is difficult to diagnose as no therapies may slow down its progression. This paper contributes a novel analytic system for Parkinson’s Disease Prediction mechanism using Improved Radial Basis Function Neural Network (IRBFNN). Particle swarm optimization (PSO) with K-means is used to find the hidden neuron’s centers to improve the accuracy of IRBFNN. The performance of RBFNN is seriously affected by the centers of hidden neurons. Conventionally K-means was used to find the centers of hidden neurons. The problem of sensitiveness to the random initial centroid in K-means degrades the performance of RBFNN. Thus, a metaheuristic algorithm called PSO integrated with K-means alleviates initial random centroid and computes optimal centers for hidden neurons in IRBFNN. The IRBFNN uses Particle swarm optimization K-means to find the centers of hidden neurons and the PSO K-means was designed to evaluate the fitness measures such as Intracluster distance and Intercluster distance. Experimentation have been performed on three Parkinson’s datasets obtained from the UCI repository. The proposed IRBFNN is compared with other variations of RBFNN, conventional machine learning algorithms and other Parkinson’s Disease prediction algorithms. The proposed IRBFNN achieves an accuracy of 98.73%, 98.47% and 99.03% for three Parkinson’s datasets taken for experimentation. The experimental results show that IRBFNN maximizes the accuracy in predicting Parkinson’s disease with minimum root mean square error.


Cite This Article

R. Shenbaga Moorthy and P. Pabitha, "Prediction of parkinson’s disease using improved radial basis function neural network," Computers, Materials & Continua, vol. 68, no.3, pp. 3101–3119, 2021.


This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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