MAGDALENA RUDZIŃSKA-RADECKA*
BIOCELL, Vol.46, No.8, pp. 1893-1901, 2022, DOI:10.32604/biocell.2022.019724
Abstract Clear cell renal cell carcinoma (KIRC) is the most common and aggressive malignancy subtype of renal neoplasm
that arises from proximal convoluted tubules. It is characterized by poor clinical outcomes and high mortality of patients due
to the lack of specific biomarkers for varying stages of the disease and no effective treatment. Proteases are associated with
the development of several malignant tumors in humans by their ability to degrade extracellular matrices, facilitating
metastasis. Herein, differentially expressed genes in KIRC cases compared to healthy kidneys were screened out from the
Gene Expression Profiling Interactive Analysis (GEPIA) database. This data was applied… More >
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