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  • Open Access

    ARTICLE

    Never Again: Online Replication of the Fading Affect Bias in the Context of Alcohol during the COVID-19 Pandemic

    Jeffrey Alan Gibbons*, Emily Anne Pappalardo, Molly Jean Nolan

    International Journal of Mental Health Promotion, Vol.28, No.7, 2026, DOI:10.32604/ijmhp.2026.080379 - 30 July 2026

    Abstract Backgrounds: The Fading Affect Bias (FAB) is the faster fading of unpleasant than pleasant affect for autobiographical event memories, which is positively and negatively related to adaptive (e.g., grit) and non-adaptive measures (e.g., depression), respectively. In contrast to the reasonable expectation that maladaptive alcohol consumption should negatively predict the FAB, no such overall relation was found in the only study to examine it. Instead, alcohol consumption positively predicted the FAB for alcohol events and negatively predicted it for non-alcohol events. We used an online procedure during the Coronavirus Disease of 2019 (COVID-19) pandemic to test if… More >

  • Open Access

    REVIEW

    Xenosialylation as immunological chimerism: a host-centered unifying model for viral and post-vaccination immune complications

    Fiorella Carnevali1,*, Maria Chiara Muollo2, Lucia Biagini2, Giacomo Rossi2

    European Cytokine Network, Vol.37, No.2, pp. 55-77, 2026, DOI:10.32604/ecn.2026.082188 - 30 June 2026

    Abstract Severe immune-mediated complications following viral infections and vaccinations, including COVID-19 and anti–SARS-CoV-2 immunization, display remarkable clinical overlap despite occurring in distinct biological contexts. In a previous hypothesis-driven work, we proposed that metabolic incorporation of the non-human sialic acid N-glycolylneuraminic acid (Neu5Gc) into human glycoconjugates—defined as xenosialylation—may contribute to post-infectious and post-vaccination immune dysregulation. We further suggest that this phenomenon may represent a form of “immunological chimerism”, in which host glycoconjugates incorporate non-self molecular structures that predispose the immune system to varying degrees of immune imbalance. In its most severe manifestation, this process may culminate in… More > Graphic Abstract

    Xenosialylation as immunological chimerism: a host-centered unifying model for viral and post-vaccination immune complications

  • Open Access

    ARTICLE

    Computational Modeling for Mortality Prediction in Medical Sciences Based on a Proto-Digital Twin Framework

    Victor Leiva1,2,*, Carlos Martin-Barreiro3,*, Viviana Giampaoli4

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.2, 2026, DOI:10.32604/cmes.2026.074800 - 26 February 2026

    Abstract Mortality prediction in respiratory health is challenging, especially when using large-scale clinical datasets composed primarily of categorical variables. Traditional digital twin (DT) frameworks often rely on longitudinal or sensor-based data, which are not always available in public health contexts. In this article, we propose a novel proto-DT framework for mortality prediction in respiratory health using a large-scale categorical biomedical dataset. This dataset contains 415,711 severe acute respiratory infection cases from the Brazilian Unified Health System, including both COVID-19 and non-COVID-19 patients. Four classification models—extreme gradient boosting (XGBoost), logistic regression, random forest, and a deep neural… More >

  • Open Access

    ARTICLE

    Enhanced COVID-19 and Viral Pneumonia Classification Using Customized EfficientNet-B0: A Comparative Analysis with VGG16 and ResNet50

    Williams Kyei*, Chunyong Yin, Kelvin Amos Nicodemas, Khagendra Darlami

    Journal on Artificial Intelligence, Vol.8, pp. 19-38, 2026, DOI:10.32604/jai.2026.074988 - 20 January 2026

    Abstract The COVID-19 pandemic has underscored the need for rapid and accurate diagnostic tools to differentiate respiratory infections from normal cases using chest X-rays (CXRs). Manual interpretation of CXRs is time-consuming and prone to errors, particularly in distinguishing COVID-19 from viral pneumonia. This research addresses these challenges by proposing a customized EfficientNet-B0 model for ternary classification (COVID-19, Viral Pneumonia, Normal) on the COVID-19 Radiography Database. Employing transfer learning with architectural modifications, including a tailored classification head and regularization techniques, the model achieves superior performance. Evaluated via accuracy, F1-score (macro-averaged), AUROC (macro-averaged), precision (macro-averaged), recall (macro-averaged), inference… More >

  • Open Access

    ARTICLE

    Increased Incidence of Congenital Heart Disease during the COVID-19 Pandemic in 492,662 Newborns: Multicenter Observational Study

    Lanqing Qu1,2,#, Jinbiao Zhang1,2,#, Wei Jiang1,2, Jiayu Zhang1,2, Die Li1, Wei Cheng3, Linghua Tao4, Hongdan Zhu5, Jing Li6, Min Xue7, Feng Chen8, Cuicui Xu9, Qiang Shu1,2,*, Weize Xu1,2,*

    Congenital Heart Disease, Vol.20, No.5, pp. 571-580, 2025, DOI:10.32604/chd.2025.066258 - 30 November 2025

    Abstract Background: Congenital heart disease (CHD) is the most common congenital anomaly, but whether the COVID-19 pandemic affects its prevalence is unknown. We aimed to compare the incidence of CHD during the COVID-19 pandemic with that before the pandemic in China. Methods: This multicenter retrospective observational study involved all newborns in seven representative cities of China between 01 September 2019, and 31 December 2021. All the newborns underwent pulse oximetry monitoring combined with cardiac murmur auscultation in the first 6 h to 72 h after birth for CHD screening. We defined fetuses born in and beyond September… More >

  • Open Access

    ARTICLE

    A Follow-Up Study on the Clinical Effectiveness and Satisfaction of an Online Mental Health Self-Care Program for Mothers in Korea

    Hyein Jeong1, Soobin Jang2, Bo-Hyoung Jang1, Chunhoo Cheon1, Taek Gyu Kim3, Chan Ho Ju3, Hwimun Kim4, Su Yong Shin5, Kyeong Han Kim6,*, Seong-Gyu Ko1,*

    International Journal of Mental Health Promotion, Vol.27, No.11, pp. 1695-1708, 2025, DOI:10.32604/ijmhp.2025.071014 - 28 November 2025

    Abstract Objectives: This study aimed to evaluate the clinical effectiveness, durability, and acceptability of a Korean medicine-based online mental health self-care program for mothers. Methods: This non-randomized comparative study evaluated the clinical effectiveness, durability, and acceptability of a Korean medicine-based online mental health self-care program for mothers. Group 1 (regular version) included 120 participants who attended one live session per week for 5 weeks, while Group 2 (shortened version) included 30 participants who completed five recorded sessions within 1 week. A total of 112 participants (93.3%) in Group 1 and all 30 participants (100%) in Group 2… More >

  • Open Access

    ARTICLE

    Experiences of COVID-19 Intensive Care Unit Physicians and Hospital Administrators: Qualitative Findings from Focus Groups

    Traci N. Adams1,#,*, Haley Belt1,#, E. Whitney Pollio2, Leah Cohen1, Roma M. Mehta1, Hetal J. Patel1, Rosechelle M. Ruggiero1, Carol S. North3

    International Journal of Mental Health Promotion, Vol.27, No.9, pp. 1369-1382, 2025, DOI:10.32604/ijmhp.2025.066495 - 30 September 2025

    Abstract Background: While quantitative research has determined that emotional distress and psychiatric illness among frontline healthcare workers increased with the COVID-19 pandemic, detailed qualitative data describing their personal experiences are needed in order to make appropriate plans to address provider mental health in future pandemics. This study aims to further explore the psychological effects of the pandemic on COVID-19 ICU clinicians and administrators through focus groups. Methods: Two separate 2-h focus groups of physicians were conducted, one with frontline faculty clinicians and another with administrators. Qualitative data analysis was conducted. Results: In September and November 2023, volunteer… More >

  • Open Access

    ARTICLE

    Impact of COVID-19 care reorganization on the prognosis of patients with bladder urothelial carcinoma: a multicentric retrospective study

    Marie Chaumel1, Nicolas Brichart2, Franck Bruyère1, Ali Bourgi1,*

    Canadian Journal of Urology, Vol.32, No.4, pp. 359-366, 2025, DOI:10.32604/cju.2025.066470 - 29 August 2025

    Abstract Background: The COVID-19 pandemic disrupted healthcare systems globally, raising concerns about delayed cancer diagnosis and treatment. In France, transurethral resection of bladder tumors (TURBT) was prioritized in national urology guidelines to ensure the timely management of urothelial carcinoma. This study aimed to assess the impact of care reorganization on tumor staging, recurrence, palliative care, and mortality in bladder cancer patients from the pre-pandemic through late-pandemic periods. Methods: We conducted a retrospective multicenter study including all patients who underwent TURBT with histologically confirmed urothelial carcinoma between April and December of 2019 (pre-pandemic), 2020 (early pandemic), 2021… More >

  • Open Access

    ARTICLE

    Living amongst the dead: How morticians coped during the COVID-19 pandemic

    Melissa Mashaba1, Curwyn Mapaling2,*, Wandile F. Tsabedze3

    Journal of Psychology in Africa, Vol.35, No.1, pp. 29-35, 2025, DOI:10.32604/jpa.2025.066007 - 30 April 2025

    Abstract The coronavirus disease (COVID-19) pandemic introduced significant psychosocial stressors for morticians in South Africa, yet their coping mechanisms remain underexplored. This study investigated how South African morticians (N = 10, Black males) coped with these stressors during the pandemic through semi-structured interviews. Interpretative phenomenological analysis (IPA) informed thematic analysis identified five themes: (i) death overload distress associated with trauma and fear of exposure; (ii) insomnia due to worry, workload, and fear of infection; (iii) stigmatisation from community avoidance and negative perceptions; (iv) social isolation and anxiety related to emotional disconnection, personal protective equipment (PPE) shortages, More >

  • Open Access

    ARTICLE

    What Factors Predict Prosocial Behavior during Social Crisis? A Cross-Sectional Study during the COVID-19 Pandemic in Spain

    Agar Marín-Morales1,2,*, Sofia Amaoui2, Carmen Fernández-Fillol2,3,4, Gustavo Carlo5, Sandra Rivas-García2,6

    International Journal of Mental Health Promotion, Vol.27, No.4, pp. 561-576, 2025, DOI:10.32604/ijmhp.2025.058881 - 30 April 2025

    Abstract Background: Prosocial behavior plays a crucial role in improving interpersonal relationships and social well-being, especially in times of crisis. The COVID-19 pandemic caused a severe humanitarian crisis, prompting governments to implement measures such as social confinement. The main objective of the study was to analyze the psychological and sociodemographic variables that may predict prosocial behavior during quarantine. Methods: The sample consisted of 172 participants from Spain, divided into two groups based on whether they reported an increase in prosocial behaviors during quarantine. An online survey was administered to analyze the psychological and sociodemographic variables. Results: Overall, More >

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