IVANA PAJIC-LIJAKOVIC*, MILAN MILIVOJEVIC
BIOCELL, Vol.47, No.11, pp. 2321-2334, 2023, DOI:10.32604/biocell.2023.043796
Abstract The biointerface dynamics influence any cancer spreading through the epithelium since it is documented in the
early stages some malignancies (like epithelial cancer). The altered rearrangement of epithelial cells has an impact on the
development of cancer. Therefore, it is necessary to comprehend the underlying biological and physical mechanisms of
this biointerface dynamics for early suppression of cancer. While the biological mechanisms include cell signaling and
gene expression, the physical mechanisms are several physical parameters such as the epithelial-cancer interfacial
tension, epithelial surface tension, and compressive stress accumulated within the epithelium. Although the
segregation of epithelia-cancer co-cultured systems was widely… More >
Graphic Abstract
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