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    Dynamic Lung Modeling and Tumor Tracking Using Deformable Image Registration and Geometric Smoothing

    Yongjie Zhang, Yiming Jing, Xinghua Liang, Guoliang Xu, Lei Dong

    Molecular & Cellular Biomechanics, Vol.9, No.3, pp. 213-226, 2012, DOI:10.3970/mcb.2012.009.213

    Abstract A greyscale-based fully automatic deformable image registration algorithm, based on an optical flow method together with geometric smoothing, is developed for dynamic lung modeling and tumor tracking. In our computational processing pipeline, the input data is a set of 4D CT images with 10 phases. The triangle mesh of the lung model is directly extracted from the more stable exhale phase (Phase 5). In addition, we represent the lung surface model in 3D volumetric format by applying a signed distance function and then generate tetrahedral meshes. Our registration algorithm works for both triangle and tetrahedral… More >

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