YINGHUA LUO^1,#, YU ZHANG^2,#, TONG ZHANG^2,#, YANNAN LI², HUI XUE², JINGLONG CAO², WENSHUANG HOU², JIAN LIU², YUHE CUI², TING XU², CHENGHAO JIN^2,3,*

BIOCELL, Vol.47, No.5, pp. 965-975, 2023, DOI:10.32604/biocell.2023.027729

Abstract Marine collagen peptides (MCPs) are natural products prepared by hydrolyzing marine collagen protein through a variety of chemical methods or enzymes. MCPs have a range of structures and biological activities and are widely present in marine species. MCPs also have a small molecular weight, are easily modified, and absorbed by the body. These properties have attracted great interest from researchers studying antioxidant, anti-tumor, and anti-aging activities. MCPs of specific molecular weights have significant anti-tumor activity and no toxic side effects. Thus, MCPs have the potential use as anti-cancer adjuvant drugs. Free radicals produced by oxidation are closely related to human… More >

Shivangi Goyal, Sreemoyee Chatterjee, Nidhi Gupta^*

Oncologie, Vol.23, No.1, pp. 89-104, 2021, DOI:10.32604/Oncologie.2021.015234

Abstract Background: Trigonella foenum-graecum Linn. has been extensively used for medicinal purposes. The current study deals with in vitro and in vivo correlation of free radical quenching activity and anticancer potential of seed extracts of Trigonella. Materials and methods: Antioxidant activity was evaluated against DPPH, NO and ABTS via in vitro radical scavenging assay. Cytotoxicity effect of Trigonella seed extract was studied in human embryonic kidney HEK 293 cell line by alamar blue assay. In vivo antioxidant activity in Swiss albino mice model was assessed by studying endogenous antioxidant enzymes such as GSH, GPx, SOD and LPO. Antitumor effect was observed… More >

Analia G. Karadayian¹, Juanita Bustamante², Silvia Lores-Arnaiz^{1, *}

BIOCELL, Vol.40, No.1, pp. 31-34, 2016, DOI:10.32604/biocell.2016.40.031

Abstract Alcohol hangover (AH) is defined as the temporary state after alcohol binge-like drinking, starting when EtOH is absent in plasma. Results from our laboratory have shown behavioral impairments and mitochondrial dysfunction in an experimental model of AH in mice. Our model consisted in a single i.p. injection of EtOH (3.8 g/kg BW) or saline solution in male and female mice, sacrificing the animals 6 hours after injection. Motor and affective behavior together with mitochondrial function and free radical production were evaluated in brain cortex and cerebellum during AH. Results showed that hangover animals exhibited a significant reduction in neuromuscular coordination,… More >

Rodrigues Costa A^1,2, PS Pereira³, MK Alves de Sousa^1,2, FC Rodrigues⁵, VR Duarte Mendes¹, KR Rodrigues Lima¹, L Marivando Barros^1,4, CM Rocha Sousa¹, MS Alcântara¹, AB Leite Cavalcante⁴, R Cruz Macedo⁵, JP Kamdem³, AE Duarte^1,2

Phyton-International Journal of Experimental Botany, Vol.87, pp. 79-86, 2018, DOI:10.32604/phyton.2018.87.079

Abstract The species Rhaphiodon echinus, known as betonica or creeping mint, is considered an infesting plant species, typical of the caatinga biome. Morphoanatomy is a very important tool to study the structure of plants, both its external and internal morphology, opening the knowledge about the production of secondary metabolites. These compounds are of great importance for scientific research, which may present themselves as the best antioxidants. Taking into account a lack of data in the literature on the essential oil of R. echinus, this study aimed to demonstrate its antioxidant activity and toxicity. In order to test this hypothesis, tests were… More >

Orozco Montes F¹, A Vázquez-Hernández², B Fenton-Navarro¹

Phyton-International Journal of Experimental Botany, Vol.88, No.1, pp. 1-10, 2019, DOI:10.32604/phyton.2019.04525

Abstract An increased interest in the antioxidant effects of medicinal plants has developed in recent years. Identifying antioxidant compounds present in medicinal plants and elucidating the mechanism by which they prevent oxidation have been the focus of the research community. We performed a systematic and exhaustive review aimed at analyzing the available data regarding the beneficial effects of secondary metabolites in plants. The result of this review is presented as a description of free radicals, as well as cellular and physiological oxidative stress, is provided. The origin and source of antioxidant compounds, and the cellular and molecular mechanism by which they… More >