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  • Open Access

    ARTICLE

    Mitochondrial DNA mutation “m.3243A>G”—Heterogeneous clinical picture for cardiologists (“m.3243A>G”: A phenotypic chameleon)

    Katharina Niedermayr1, Gerhard Pölzl2, Sabine Scholl‐Bürgi1, Christine Fauth3, Ulrich Schweigmann1, Edda Haberlandt1, Ursula Albrecht1, Manuela Zlamy1, Wolfgang Sperl4, Johannes A. Mayr4, Daniela Karall1

    Congenital Heart Disease, Vol.13, No.5, pp. 671-677, 2018, DOI:10.1111/chd.12634

    Abstract Objective: In general, a mitochondrial disorder is diagnosed on the basis of symptom combinations and confirmed by genetic findings. However, patients carrying the m.3243A>G mutation in the mitochondrial tRNA leucine 1 (MT‐TL1) do not always meet all the proposed criteria for the most frequently encountered mitochondrial syndrome “MELAS,” an acronym for Mitochondrial Encephalomyopathy, Lactic Acidosis, and at least one Stroke‐like episode. We here present various phenotypic characteristics of the mitochondrial mutation m.3243A>G with particular focus on cardiac manifestations.
    Methods and Results: We followed nine patients (1 month to 68 years old; median 42 years; four female and five male) from… More >

  • Open Access

    ARTICLE

    Simulation of Solid Particle Interactions Including Segregated Lamination by Using MPS Method

    Kyung Sung Kim1, Moo-Hyun Kim2,*, Hakun Jang3, Hee Chen Cho4

    CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.1, pp. 11-29, 2018, DOI:10.31614/cmes.2018.00199

    Abstract A new MPS (Moving Particle Semi-implicit) method is developed to simulate the behaviors and interactions of multiple fine solid particles as a continuum. As fluid particles are affected by viscosity, so solid particles are affected by friction. The solid particle dynamics for landslides, dumping, and gravity sorting etc. which can be difficult to simulate using conventional MPS methods, are modeled in this paper using the developed multi-solid-particle MPS method that benefits from drawing comparisons with the corresponding fluid particle behaviors. The present MPS results for dumping solid particles are verified against the corresponding DEM (Discrete… More >

  • Open Access

    ARTICLE

    Lattice Boltzmann Simulation of a Gas-to-Solid Reaction and Precipitation Process in a Circular Tube

    Matthew D. Lindemer1, Suresh G. Advani2,*, Ajay K. Prasad2

    CMES-Computer Modeling in Engineering & Sciences, Vol.117, No.3, pp. 527-553, 2018, DOI:10.31614/cmes.2018.00481

    Abstract The lattice Boltzmann method (LBM) is used to simulate the growth of a solid-deposit on the walls of a circular tube resulting from a gas-to-solid reaction and precipitation process. This process is of particular interest for the design of reactors for the production of hydrogen by the heterogeneous hydrolysis of steam with Zn vapor in the Zn/ZnO thermochemical cycle. The solid deposit of ZnO product on the tube wall evolves in time according to the temporally- and axially-varying convective-diffusive transport and reaction of Zn vapor with steam on the solid surface. The LBM is well-suited… More >

  • Open Access

    ARTICLE

    A Spark Scheduling Strategy for Heterogeneous Cluster

    Xuewen Zhang1, Zhonghao Li1, Gongshen Liu1,*, Jiajun Xu1, Tiankai Xie2, Jan Pan Nees1

    CMC-Computers, Materials & Continua, Vol.55, No.3, pp. 405-417, 2018, DOI:10.3970/cmc.2018.02527

    Abstract As a main distributed computing system, Spark has been used to solve problems with more and more complex tasks. However, the native scheduling strategy of Spark assumes it works on a homogenized cluster, which is not so effective when it comes to heterogeneous cluster. The aim of this study is looking for a more effective strategy to schedule tasks and adding it to the source code of Spark. After investigating Spark scheduling principles and mechanisms, we developed a stratifying algorithm and a node scheduling algorithm is proposed in this paper to optimize the native scheduling More >

  • Open Access

    ARTICLE

    INFLUENCE OF CONVECTIVE BOUNDARY CONDITION ON NONLINEAR THERMAL CONVECTION FLOW OF A MICROPOLAR FLUID SATURATED POROUS MEDIUM WITH HOMOGENEOUS-HETEROGENEOUS REACTIONS

    Chetteti RamReddya,†, Teegala Pradeepaa

    Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-10, 2017, DOI:10.5098/hmt.8.6

    Abstract A numerical approach has been used to analyze the effects of homogeneous-heterogeneous reaction and nonlinear density temperature variation over a vertical plate in an incompressible micropolar fluid flow saturated Darcy porous medium. In addition, convective boundary condition is incorporated in a micropolar fluid model. The similarity representation for the set of partial differential equations is attained by applying Lie group transformations. The resulting non-dimensional equations are worked out numerically by spectral quasi-linearization method. Less temperature and wall couple stress coefficient, but more velocity, skin friction, species concentration, and heat transfer rate are noticed by enhancing More >

  • Open Access

    ARTICLE

    EFFECTS OF HOMOGENEOUS-HETEROGENEOUS CHEMICAL REACTION AND SLIP VELOCITY ON MHD STAGNATION FLOW OF A MICROPOLAR FLUID OVER A PERMEABLE STRETCHING/SHRINKING SURFACE EMBEDDED IN A POROUS MEDIUM

    P. Bala Anki Reddya,*, S. Suneethab

    Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-11, 2017, DOI:10.5098/hmt.8.24

    Abstract We report on a mathematical model for analyzing the effects of homogeneous-heterogeneous chemical reaction and slip velocity on the MHD stagnation point flow of electrically conducting micropolar fluid over a stretching/shrinking surface embedded in a porous medium. The governing boundary layer coupled partial differential equations are transformed into a system of non-linear ordinary differential equations, which are solved numerically using the MATLAB bvp4c solver. The effects of physical and fluid parameters such as the stretching parameter, micropolar parameter, permeability parameter, strength of homogeneous and heterogeneous reaction parameter on the velocity and concentration are analyzed, and More >

  • Open Access

    Synthesis of Methyl Lactate from Glycerol Using Sn-Beta Zeolite

    Wenjie Dong, Chenlu Wang, Minyan Gu, Long Yang, Zheng Shen*, Yalei Zhang*

    Journal of Renewable Materials, Vol.5, Suppl.1, pp. 22-30, 2017, DOI:10.7569/JRM.2017.634126

    Abstract Lactic acid can not only be used to produce multiple chemicals, but can also be the building block for biodegradable and biocompatible polylactic acid identified as a renewable resource. As a by-product in biodiesel production, the glycerol yield increases with a rapid expansion of biodiesel. However, in the chemical and environmental fields it is still a great challenge to produce lactic acid or methyl lactate from glycerol. Herein, Sn-Beta zeolite was prepared through solid-state ion exchange (Sn-Beta SSIE) and was tested for base-free one-pot catalytic selective oxidation of glycerol into methyl lactate in methanol. The More >

  • Open Access

    ARTICLE

    Valorization of Citrus Waste: Use in Catalysis for the Oxidation of Sulfides

    María Belén Colombo Migliorero, Valeria Palermo*, Patricia Graciela Vázquez, Gustavo Pablo Romanelli

    Journal of Renewable Materials, Vol.5, No.3-4, pp. 167-173, 2017, DOI:10.7569/JRM.2017.634108

    Abstract The utilization and valorization of industrial waste is an effective strategy for environmental protection. Since the juice industry generates a huge amount of citrus waste, we studied the application of thermally treated orange peel in catalysis. On the other hand, Keggin heteropolyacids are excellent oxidant catalysts used as a replacement for conventional oxidants; however, their solubility in polar solvents and the low specific area limit their use as heterogeneous catalysts. The utilization of treated orange peel as heteropolyacid support for the selective oxidation of sulfides is presented here. Firstly, orange peel was thermally treated, and More >

  • Open Access

    ARTICLE

    DUAL SOLUTIONS FOR HEAT AND MASS TRANSFER IN MHD JEFFREY FLUID IN THE PRESENCE OF HOMOGENEOUSHETEROGENEOUS REACTIONS

    C. S. K. Rajua , N. Sandeepa, J. Prakashb,1

    Frontiers in Heat and Mass Transfer, Vol.7, pp. 1-8, 2016, DOI:10.5098/hmt.7.14

    Abstract In this study, we analyzed the effects of nonlinear thermal radiation and induced magnetic field on steady two-dimensional incompressible flow of Jeffrey fluid flow past a stretching/shrinking surface in the presence of homogeneous-heterogeneous reactions. For physical relevance in this study we analyzed the behavior of homogeneous and heterogeneous profiles individually. The transformed governing equations with the help of similarity variables are solved numerically via Runge-Kutta and Newton’s method. We obtained better accuracy of the present results by differentiating with the existed published literature. The effect of pertinent parameters on velocity, induced magnetic field, temperature and More >

  • Open Access

    ARTICLE

    Excluded Volumes of Anisotropic Convex Particles in Heterogeneous Media: Theoretical and Numerical Studies

    Wenxiang Xu1,2,3,4, Ganquan Yang5, Peng Lan2, Huaifa Ma1

    CMC-Computers, Materials & Continua, Vol.52, No.1, pp. 25-40, 2016, DOI:10.3970/cmc.2016.052.025

    Abstract Understanding the excluded volume of anisotropic particle is of great importance in the evaluation of continuum percolation and random packing behaviors of soft/hard particle systems in heterogeneous disordered media. In this work, we obtain the excluded volumes of several anisotropic convex particles including prolate spheroids, oblate spheroids, spherocylinders, and Platonic particles, using theoretical and numerical approaches. According to the second virial coefficient, we first present a theoretical scheme for determining the excluded volumes of anisotropic particles. Also, the mean tangent diameters of anisotropic convex particles are formulated by the quantitative stereology. Subsequently, Monte Carlo simulations… More >

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