MERYEM A. ABDESSALEM, SIRIN A. ADHAM^*

Oncology Research, Vol.33, No.1, pp. 27-44, 2025, DOI:10.32604/or.2024.056955 - 20 December 2024

Abstract Nanotechnology in cancer therapy has significantly advanced treatment precision, effectiveness, and safety, improving patient outcomes and personalized care. Engineered smart nanoparticles and cell-based therapies are designed to target tumor cells, precisely sensing the tumor microenvironment (TME) and sparing normal cells. These nanoparticles enhance drug accumulation in tumors by solubilizing insoluble compounds or preventing their degradation, and they can also overcome therapy resistance and deliver multiple drugs simultaneously. Despite these benefits, challenges remain in patient-specific responses and regulatory approvals for cell-based or nanoparticle therapies. Cell-based drug delivery systems (DDSs) that primarily utilize the immune-recognition principle between… More > Graphic Abstract

SOROUSH SOLEYMANI¹, MOHAMMAD DOROUDIAN^2,*, MAHDIEH SOEZI^3,4, ALI BELADI⁵, KIARASH ASGARI², ASO MOBARAKSHAHI², ARYANA AGHAEIPOUR², RONAN MACLOUGHLIN^6,7,8,*

Oncology Research, Vol.33, No.1, pp. 15-26, 2025, DOI:10.32604/or.2024.053069 - 20 December 2024

Abstract Brain metastasis and primary glioblastoma multiforme represent the most common and lethal malignant brain tumors. Its median survival time is typically less than a year after diagnosis. One of the major challenges in treating these cancers is the efficiency of the transport of drugs to the central nervous system. The blood-brain barrier is cooperating with advanced stages of malignancy. The blood-brain barrier poses a significant challenge to delivering systemic medications to brain tumors. Nanodrug delivery systems have emerged as promising tools for effectively crossing this barrier. Additionally, the development of smart nanoparticles brings new hope More >

AMOURA M. ABOU-EL-NAGA¹, SHAKER A. MOUSA², FAYEZ ALTHOBAITI³, EMAN FAYAD^3,*, ENGY S. FAHIM¹

BIOCELL, Vol.48, No.12, pp. 1835-1837, 2024, DOI:10.32604/biocell.2024.054569 - 30 December 2024

Abstract This article has no abstract. More >

Abdul Ghafoor¹, Maria Latif², Shafaqat Ali^2,3,*, Muhammad Munir^4,*, Muhammad Naeem Sattar⁵, Mohammed Ali Alshehri⁶

Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2683-2705, 2024, DOI:10.32604/phyton.2024.055898 - 30 November 2024

Abstract Heavy metal pollution in agricultural soils is a significant challenge for global food production and human health with the increasing industrialization and urbanization. There is a concern about introducing innovative techniques that are eco-friendly, cost-effective, and have the potential to alleviate metals, enhance crop growth, and protect plants against various environmental threats. For this, nanotechnology is one of the promising solutions having various applications in almost every field of life. This review explores various nano-based strategies that use nanoparticles (NPs) to lessen the harmful effects that heavy metals have on plants. Incorporated literature including published… More >

Erdong Shen¹, Ting Pan¹, Pan Guo¹, Ke Chen¹, Rui Xu¹, Mei Yang¹, Dahe Zhan¹, Fang Fang¹, Qinghui Wu^1,*, Jianbing Hu^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-3, 2024, DOI:10.32604/icces.2024.012772

Abstract Objective
This study investigates the synergistic effects of a novel multifunctional nanoparticle on gastric cancer treatment through photothermal therapy, chemotherapy, and immunotherapy.

Method
Synthesize hollow mesoporous Prussian blue nanoparticles and load them with luteolin. Use exosomes to encapsulate the nanoparticles and modify the surface of the targeted peptide GX1. Detect the morphology of nanoparticles using a nanoparticle size analyzer and transmission electron microscopy. Use Coomassie Brilliant Blue to detect the effect of extracellular vesicle encapsulation. Detect the thermal conversion efficiency of nanoparticles under specific laser irradiation through infrared and ultraviolet spectroscopy, as well as the release rate… More >

JYOTHI B. NAIR^1,2, ANU MARY JOSEPH³, SANOOP P.⁴, MANU M. JOSEPH^5,*

BIOCELL, Vol.48, No.11, pp. 1579-1602, 2024, DOI:10.32604/biocell.2024.054879 - 07 November 2024

Abstract Nanoparticles represent a heterogeneous collection of materials, whether natural or synthetic, with dimensions aligning in the nanoscale. Because of their intense manifestation with the immune system, they can be harvested for numerous bio-medical and biotechnological advancements mainly in cancer treatment. This review article aims to scrutinize various types of nanoparticles that interact differently with immune cells like macrophages, dendritic cells, T lymphocytes, and natural killer (NK) cells. It also underscores the importance of knowing how nanoparticles influence immune cell functions, such as the production of cytokines and the presentation of antigens which are crucial for… More >

Mudasar Zafar^1,2,3,*, Hamzah Sakidin¹, Abida Hussain¹, Loshini Thiruchelvam⁴, Mikhail Sheremet⁵, Iskandar Dzulkarnain³, Roslinda Nazar⁶, Abdullah Al-Yaari¹, Rizwan Safdar^7,8

CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1193-1211, 2024, DOI:10.32604/cmes.2024.049259 - 27 September 2024

Abstract This study aims to formulate a steady-state mathematical model for a three-dimensional permeable enclosure (cavity) to determine the oil extraction rate using three distinct nanoparticles, SiO₂, Al₂O₃, and Fe₂O₃, in unconventional oil reservoirs. The simulation is conducted for different parameters of volume fractions, porosities, and mass flow rates to determine the optimal oil recovery. The impact of nanoparticles on relative permeability ( and water is also investigated. The simulation process utilizes the finite volume ANSYS Fluent. The study results showed that when the mass flow rate at the inlet is low, oil recovery goes up. In addition, More >

Heru Suryanto^1,2,*, Daimon Syukri³, Fredy Kurniawan⁴, Uun Yanuhar⁵, Joseph Selvi Binoj⁶, Sahrul Efendi², Fajar Nusantara², Jibril Maulana⁷, Nico Rahman Caesar⁵, Komarudin Komarudin²

Journal of Renewable Materials, Vol.12, No.9, pp. 1605-1624, 2024, DOI:10.32604/jrm.2024.054047 - 25 September 2024

Abstract Utilizing biomass waste as a potential resource for cellulose production holds promise in mitigating environmental consequences. The current study aims to utilize pineapple biowaste extract in producing bacterial cellulose acetate-based membranes with magnetic nanoparticles (Fe₃O₄ nanoparticles) through the fermentation and esterification process and explore its characteristics. The bacterial cellulose fibrillation used a high-pressure homogenization procedure, and membranes were developed incorporating 0.25, 0.50, 0.75, and 1.0 wt.% of Fe₃O₄ nanoparticles as magnetic nanoparticle for functionalization. The membrane characteristics were measured in terms of Scanning Electron Microscope, X-ray diffraction, Fourier Transform Infrared, Vibrating Sample Magnetometer, antibacterial activity, bacterial… More > Graphic Abstract

Ankitkumar Patel¹, Srivathsan Vasudevan^1,*, Satya Bulusu^2,*

CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 3803-3818, 2024, DOI:10.32604/cmc.2024.052851 - 12 September 2024

Abstract Molecular Dynamics (MD) simulation for computing Interatomic Potential (IAP) is a very important High-Performance Computing (HPC) application. MD simulation on particles of experimental relevance takes huge computation time, despite using an expensive high-end server. Heterogeneous computing, a combination of the Field Programmable Gate Array (FPGA) and a computer, is proposed as a solution to compute MD simulation efficiently. In such heterogeneous computation, communication between FPGA and Computer is necessary. One such MD simulation, explained in the paper, is the (Artificial Neural Network) ANN-based IAP computation of gold (Au₁₄₇ & Au₃₀₉) nanoparticles. MD simulation calculates the forces… More >

Song Lu¹, Jianjun Guo², Richard Ansah Herman¹, Xinyi Wu¹, Lin Ma¹, Guohua Wu^1,*

Journal of Renewable Materials, Vol.12, No.6, pp. 1043-1055, 2024, DOI:10.32604/jrm.2024.051767 - 02 August 2024

Abstract Silk is widely used in the production of high-quality textiles. At the same time, the amount of silk textiles no longer in use and discarded is increasing, resulting in significant waste and pollution. This issue is of great concern in many countries where silk is used. Hydrogen peroxide as a naturally occurring compound is an important indicator of detection in both biology and the environment. This study aims to develop a composite fiber with hydrogen peroxide-sensing properties using discarded silk materials. To achieve this goal, firstly, polydopamine (PDA) was used to encapsulate the ZnFeO NPs… More > Graphic Abstract