CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.3, pp. 1505-1522, 2021, DOI:10.32604/cmes.2021.019500 - 25 November 2021

Abstract This article has no abstract. More >

MIZUNA YANO¹, YUTA UMEHARA¹, TOMOKAZU KUDO¹, TAKAO NAKAMURA², TADASHI KOSAWADA¹, ATSUYOSHI NISHINA³, MASAKI SAZUKA⁴, DAISUKE SATO^1,*, ZHONGGANG FENG^1,*

BIOCELL, Vol.45, No.5, pp. 1213-1229, 2021, DOI:10.32604/biocell.2021.016281 - 12 July 2021

Abstract While fatty acids play essential roles in the physiology of the myocardium, conventional culture media contain little lipid. We previously revealed that rat neonatal myocardium mainly contains docosahexaenoic (DHA), linoleic (LA), and arachidonic (AA) acids as polyunsaturated fatty acids (PUFAs), and these contents in cultured cardiomyocytes derived from fetal rats were markedly lower than those in the neonatal myocardium. In this study, we first assessed the effects of supplementation of DHA, LA, or AA on the fatty acid contents and the percentage change of contractile area in primarily cultured rat cardiomyocytes. Based on this assessment,… More >

Leonard G. Gomella

Canadian Journal of Urology, Vol.27, No.1, pp. 10067-10067, 2020

Abstract This article has no abstract. More >

Tsung-Kun Chang^*†, Tzu-Chieh Yin^‡§, Wei-Chih Su^*†, Hsiang-Lin Tsai^*¶, Ching-Wen Huang^*¶, Yen-Cheng Chen^*, Ching-Chun Li^*, Po-Jung Chen^*, Cheng-Jen Ma^*§, Kuo-Hsiang Chuang^#, Tian-Lu Cheng^**, Jaw-Yuan Wang^{*†¶††‡‡§§}

Oncology Research, Vol.28, No.7-8, pp. 801-809, 2020, DOI:10.3727/096504021X16218531628569

Abstract Irinotecan, a topoisomerase inhibitor, is a common cytotoxic agent prescribed for metastatic colorectal cancer (mCRC) patients. Diarrhea is the most common adverse event (AE). The underlying mechanism of irinotecaninduced diarrhea is intestinal mucosal damage caused by SN-38 (active metabolite of irinotecan) hydrolyzed from SN-38G (inactive metabolite) by bacterial -glucuronidase ( G). According to an animal study, silymarin reduces the activity of bacterial G without impairing antitumor efficacy. We conducted a prospective openlabel pilot study to evaluate the effect of silymarin as supplementation in reducing toxicities of mCRC patients undergoing irinotecan-based chemotherapy. We enrolled and randomized More >

Rohit S. Loomba^1,2, Enrique G. Villarreal^3,*, Riddhi Patel¹, Samantha Udarbe¹, Vincent Dorsey¹, Kristen Nelson-McMillan^1,4, Saul Flores^5,6

Congenital Heart Disease, Vol.15, No.6, pp. 447-455, 2020, DOI:10.32604/CHD.2020.012927 - 02 November 2020

Abstract Introduction: In children, data on the effects on carnitine supplementation and myocardial function are limited. A few studies have investigated the relationship between serum carnitine levels in the setting of depressed cardiac function and have demonstrated possible benefits. As such, this systematic review and meta-analyses aimed to assess the effects carnitine supplementation on left ventricular function. Materials and Methods: A systematic review of the literature was performed to identify full text manuscripts in English. PubMed, EMBASE, and the Cochrane databases were queried. Studies were included with data from pediatric patients, that used carnitine supplementation and included preand… More >

Zahoor Ahmad^1,*, Ejaz Ahmad Waraich², Celaleddin Barutçular¹, Akbar Hossain³, Murat Erman⁴, Fatih ÇIĞ⁴, Hany Gharib⁵, Ayman EL Sabagh^{4, 5, *}

Phyton-International Journal of Experimental Botany, Vol.89, No.3, pp. 529-539, 2020, DOI:10.32604/phyton.2020.09143 - 22 June 2020

Abstract The main objective of the research is to assess the role of foliar application of silicon (Si) for enhancing the survival ability of wheat under drought stress through improving its morphology, physicochemical and antioxidants activities. Treatments were five doses of Si at the rate of 2, 4, 6 and 8 mM and a control. After completion of seeds germination, pots were divided into four distinct groups at various field capacity (FC) levels, such as 100% FC (well-irrigated condition), 75% FC (slight water deficit), 50% FC (modest water deficit) and 25% FC (severe water deficit stress… More >

Sara Youssry¹, Maher A. Kamel²

European Cytokine Network, Vol.30, No.4, pp. 135-143, 2019, DOI:10.1684/ecn.2019.0437

Abstract Background and aims: Chronic hepatic inflammation is an important pathogenic mediator of nonalcoholic fatty liver disease (NAFLD) that contributes to disease severity. It is commonly suggested that autophagy dysfunction may be an underlying cause of nonalcoholic fatty liver disease. However, the exact role of autophagy in lipid metabolism remains controversial. There has been a growing interest in the role of folate supplementation for the treatment and/or prevention of NAFLD. We aimed in this study to investigate the effects of different doses of folate supplementation on several immune markers and autophagy trying to explore the complex… More >

Yuval Freifeld, Yair Lotan

Canadian Journal of Urology, Vol.24, No.4, pp. 8902-8902, 2017

Abstract This article has no abstract. More >

Timothy D. Lyon¹, Robert M. Turner II¹, Dawn McBride¹, Li Wang², Jeffrey R. Gingrich¹, Ronald L. Hrebinko¹, Bruce L. Jacobs¹, Benjamin J. Davies¹, Tatum V. Tarin¹

Canadian Journal of Urology, Vol.24, No.4, pp. 8895-8901, 2017

Abstract Introduction: To investigate the use of a high-arginine immunonutrient supplement prior to radical cystectomy for bladder cancer.
Materials and methods: We recruited 40 patients to consume a total of four high-arginine immunonutrient shakes per day for 5 days prior to radical cystectomy. The primary outcome measures were safety, tolerability and adherence to the supplementation regimen. Ninety-day postoperative outcomes were also compared between supplemented patients and a cohort of 104 prospectively identified non-supplemented radical cystectomy patients. Multivariable logistic regression models were used to compare overall complications, infectious complications, and readmission rates between groups.
Results: There were no serious adverse… More >

Wojciech Kubissa¹, Roman Jaskulski¹, Pavel Reiterman^2*

Journal of Renewable Materials, Vol.5, Suppl.1, pp. 53-61, 2017, DOI:10.7569/JRM.2017.634103

Abstract This article deals with an experimental study concerning the development of concrete mixtures with significant ecological benefits. The studied concrete mixtures were based on blast-furnace cement, with an additional application of supplementary cementitious materials—fly ash, metakaolin, and silica fume and fluidized fly ash. Coarse aggregate in the form of crushed concrete was applied for all studied concrete mixtures. The experimental program was primarily focused on the assessment of the durability properties of the studied mixtures in terms of mechanical tests, absorption tests, chloride migration coefficient tests, water penetration tests, and accelerated carbonation depth tests. The More >