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  • Open Access

    REVIEW

    Wood By-Products as UV Protection: A Consequence Review

    Naglaa Salem El‑Sayed, Mohamed Hasanin, Samir Kamel*

    Journal of Renewable Materials, Vol.12, No.4, pp. 699-720, 2024, DOI:10.32604/jrm.2024.049118

    Abstract In recent decades, the ozone layer has suffered considerable damage, increasing the entry of ultraviolet (UV) light into the atmosphere and reaching the earth’s surface, negatively affecting life. Accordingly, researchers aimed to solve this problem by synthesizing advanced UV-shielding materials. On the other hand, developing an easy and green strategy to prepare functional materials without standing properties based on naturally abundant and environmentally friendly raw materials is highly desirable for sustainable development. Because biomass-derived materials are sustainable and biodegradable, they present a promising substitute for petroleum-based polymers. The three main structural constituents of the plant More > Graphic Abstract

    Wood By-Products as UV Protection: A Consequence Review

  • Open Access

    REVIEW

    New Problems of Boiler Corrosion after Coupling Combustion of Coal and Biomass and Anti-Corrosion Technologies

    Lei Wang1, Ziran Ma1,*, Chunlin Zhao1, Jiali Zhou1, Hongyan Wang1, Ge Li1, Ningling Zhou2

    Journal of Renewable Materials, Vol.12, No.4, pp. 799-814, 2024, DOI:10.32604/jrm.2024.047343

    Abstract This study explores the corrosion issues arising from the coupled combustion of coal and biomass and proposes potential solutions. Biomass, as a renewable energy source, offers advantages in energy-saving and carbon reduction. However, the corrosive effects of alkali metal compounds, sulfur (S) and chlorine (Cl) elements in the ash after combustion cannot be underestimated due to the high volatile content of biomass fuels. We investigate the corrosion mechanisms, as well as the transfer of Cl and alkali metal elements during this process. Comparative corrosion analyses are conducted among coal-fired boilers, pure biomass boilers and boilers… More >

  • Open Access

    ARTICLE

    An Innovative Technique to Measure Lateral Pressure of Self-Compacting Concrete Using Fiber Bragg Grating Sensor

    Pshtiwan Shakor1,2,*, Nadarajah Gowripalan3, Paul Rocker4

    Structural Durability & Health Monitoring, Vol.18, No.4, pp. 395-408, 2024, DOI:10.32604/sdhm.2024.049366

    Abstract Self-compacting concrete (SCC) is the most flowable concrete type that exerts high pressure on formwork. SCC is the most commonly used concrete globally for construction applications due to its cost-effectiveness. However, to make a formwork resist the exerted lateral pressure of SCC, it is required to have a suitable design for formwork. This paper presents a novel approach on how could create and prepare the Fiber Bragg Grating (FBG) optics using as a sensor to measure lateral pressure and temperature of SCC. To ensure the FBG sensor works properly a validated methodology is conducted. In More > Graphic Abstract

    An Innovative Technique to Measure Lateral Pressure of Self-Compacting Concrete Using Fiber Bragg Grating Sensor

  • Open Access

    ARTICLE

    Rapid and Accurate Identification of Concrete Surface Cracks via a Lightweight & Efficient YOLOv3 Algorithm

    Haoan Gu1, Kai Zhu1, Alfred Strauss2, Yehui Shi3,4, Dragoslav Sumarac5, Maosen Cao1,*

    Structural Durability & Health Monitoring, Vol.18, No.4, pp. 363-380, 2024, DOI:10.32604/sdhm.2024.042388

    Abstract Concrete materials and structures are extensively used in transformation infrastructure and they usually bear cracks during their long-term operation. Detecting cracks using deep-learning algorithms like YOLOv3 (You Only Look Once version 3) is a new trend to pursue intelligent detection of concrete surface cracks. YOLOv3 is a typical deep-learning algorithm used for object detection. Owing to its generality, YOLOv3 lacks specific efficiency and accuracy in identifying concrete surface cracks. An improved algorithm based on YOLOv3, specialized in the rapid and accurate identification of concrete surface cracks is worthy of investigation. This study proposes a tailored… More >

  • Open Access

    REVIEW

    Molecular and cellular mechanisms of neuroprotection by oligopeptides from snake venoms

    CARLOS ALBERTO-SILVA*, BRENDA RUFINO DA SILVA

    BIOCELL, Vol.48, No.6, pp. 897-904, 2024, DOI:10.32604/biocell.2024.050443

    Abstract Venom snake-derived peptides have multiple biochemical, pharmacological, and toxicological profiles, allowing for the discovery of new medicinal products and therapeutic applications. This review specifically examines the fundamental elements of neuroprotection offered by different oligopeptides derived from snake venom. It also includes a brief evaluation of short peptides that are being considered as potential therapeutic agents. Proline-rich peptides and tryptophyllin family peptides isolated from the crude venom of Viperidae family snakes, specifically Bothrops atrox, Bothrops jararaca, and Bothrops moojeni, have been shown to have pro-survival properties, the ability to reduce oxidative stress, and the ability to promote cell viability More >

  • Open Access

    ARTICLE

    Bhlhe40 protects cochlear hair cell-like HEI-OC1 cells against HO‑triggered oxidative injury

    LITING WEN#, XIAOXIA ZENG#, PEIXIONG CHEN, DAPENG ZHAO, YANGYANG LI, XIANHAI ZENG*

    BIOCELL, Vol.48, No.6, pp. 991-999, 2024, DOI:10.32604/biocell.2024.050219

    Abstract Background: Cochlear hair cell injury is a common pathological feature of hearing loss. The basic helix-loop-helix family, member e40 (Bhlhe40), a gene belonging to the basic helix-loop-helix (bHLH) family, exhibits strong transcriptional repression activity. Methods: Oxidative damage, in House Ear Institute-Organ of Corti 1 (HEI‑OC1) cells, was caused using hydrogen peroxide (HO). The Ad-Bhlhe40 particles were constructed to overexpress Bhlhe40 in HEI-OC1 cells. Various assays including cell counting kit-8 (CCK-8), terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay (TUNEL), flow cytometry, immunofluorescence, and corresponding commercial kits were employed to investigate the impacts of Bhlhe40 on cell viability, apoptosis,… More > Graphic Abstract

    <i>Bhlhe40</i> protects cochlear hair cell-like HEI-OC1 cells against HO‑triggered oxidative injury

  • Open Access

    ARTICLE

    An Intrusion Detection Method Based on a Universal Gravitation Clustering Algorithm

    Jian Yu1,2,*, Gaofeng Yu3, Xiangmei Xiao1,2, Zhixing Lin1,2

    Journal of Cyber Security, Vol.6, pp. 41-68, 2024, DOI:10.32604/jcs.2024.049658

    Abstract With the rapid advancement of the Internet, network attack methods are constantly evolving and adapting. To better identify the network attack behavior, a universal gravitation clustering algorithm was proposed by analyzing the dissimilarities and similarities of the clustering algorithms. First, the algorithm designated the cluster set as vacant, with the introduction of a new object. Subsequently, a new cluster based on the given object was constructed. The dissimilarities between it and each existing cluster were calculated using a defined difference measure. The minimum dissimilarity was selected. Through comparing the proposed algorithm with the traditional Back More >

  • Open Access

    ARTICLE

    Regorafenib Plus FOLFIRI With Irinotecan Dose Escalated According to Uridine Diphosphate Glucuronosyltransferase 1A1 Genotyping in Patients With Metastatic Colorectal Cancer

    Cheng-Jen Ma*†‡, Ching-Wen Huang*‡§, Yung-Sung Yeh*†¶, Hsiang-Lin Tsai*§#**, Huang-Ming Hu††‡‡, I-Chen Wu††‡‡, Tian-Lu Cheng§§¶¶, Jaw-Yuan Wang*†‡§**¶¶

    Oncology Research, Vol.25, No.5, pp. 673-679, 2017, DOI:10.3727/97818823455816X14786040691928

    Abstract We analyzed the results of previously treated patients with metastatic colorectal cancer (mCRC) who received regorafenib plus FOLFIRI with the irinotecan dose escalation on the basis of uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) genotyping. Thirteen patients with previously treated mCRC were subjected to UGT1A1 genotyping between October 2013 and June 2015 and were administered regorafenib plus FOLFIRI with irinotecan dose escalation. Patients with UGT1A1*1/*1 and *1/*28 genotypes were administered 180 mg/m2 of irinotecan, whereas those with the UGT1A1*28/*28 genotype were administered 120 mg/m2 of irinotecan. For all patients, the irinotecan dose was increased by 30 mg/m2 every… More >

  • Open Access

    ARTICLE

    Validity of Osteoprotegerin and Receptor Activator of NF-κB Ligand for the Detection of Bone Metastasis in Breast Cancer

    Gamal A. Elfar*†, Mohamed A. Ebrahim, Nehal M. Elsherbiny*, Laila A. Eissa*

    Oncology Research, Vol.25, No.4, pp. 641-650, 2017, DOI:10.3727/096504016X14768398678750

    Abstract Osteoprotegerin (OPG) is a robust antiresorptive molecule that acts as a decoy receptor for the receptor activator of nuclear factor kB ligand (RANKL), the mediator of osteoclastogenesis. This study was designed to explore the possible role of serum OPG and RANKL in detecting bone metastasis in breast cancer and its interaction with clinicopathologic parameters. Serum levels of RANKL and OPG were estimated in 44 metastatic and 36 nonmetastatic breast cancer patients using ELISA kits. Serum OPG levels were significantly reduced in patients with bone metastasis and correlated negatively with the number of bone lesions and… More >

  • Open Access

    ARTICLE

    Detection of Necroptosis in Ligand-Mediated and Hypoxia-Induced Injury of Hepatocytes Using a Novel Optic Probe-Detecting Receptor-Interacting Protein (RIP)1/RIP3 Binding

    Sanae Haga*, Akira Kanno, Takeaki Ozawa, Naoki Morita§, Mami Asano,¶ and Michitaka Ozaki

    Oncology Research, Vol.26, No.3, pp. 503-513, 2018, DOI:10.3727/096504017X15005102445191

    Abstract Liver injury is often observed in various pathological conditions including posthepatectomy state and cancer chemotherapy. It occurs mainly as a consequence of the combined necrotic and apoptotic types of cell death. In order to study liver/hepatocyte injury by the necrotic type of cell death, we studied signal-regulated necrosis (necroptosis) by developing a new optic probe for detecting receptor-interacting protein kinase 1 (RIP)/RIP3 binding, an essential process for necroptosis induction. In the mouse hepatocyte cell line, TIB-73 cells, TNF-a/cycloheximide (T/C) induced RIP1/3 binding only when caspase activity was suppressed by the caspase-specific inhibitor z-VAD-fmk (zVAD). T/C/zVAD-induced… More >

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