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    Comparison of Hemodynamic Endpoints between Normal Subject and Tetralogy Patient Using Womersley Velocity Profile and MR Based Flow Measurements

    Ashish Das, William M. Gottliebson†,‡, Madhura Karve, Rupak Banerjee∗,§,¶

    Molecular & Cellular Biomechanics, Vol.8, No.1, pp. 21-42, 2011, DOI:10.3970/mcb.2011.008.021

    Abstract Right ventricular (RV) enlargement and pulmonary valve insufficiency (PI) are well-known, unavoidable long term sequelae encountered by patients who undergo tetralogy of Fallot (TOF) surgery. Despite their lifelong need for cardiac surveillance and occasional re-intervention, there is a paucity of numerical data characterizing blood flows in their pulmonary arteries (PA). Specifically, although PA regurgitation is well-known to be ubiquitously present in adult repaired TOF (rTOF) patients yet, there have been only limited numerical studies to fully characterize this process. The few studies available have utilized idealized, simplistic geometric models or overly simplistic boundary conditions that… More >

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