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  • Open Access


    Analysis on Characteristics and Nursing Points of Surgical and Interventional Treatment for Elderly Cerebral Aneurysm

    Haiying You1, Jing Li2, Xiaojie Wang3, Guodong Zhang4, Juan Yang5,*

    Oncologie, Vol.22, No.4, pp. 235-244, 2020, DOI:10.32604/oncologie.2020.014123

    Abstract Objective. The purpose was to explore the characteristics and nursing points of surgical and interventional treatment for elderly cerebral aneurysm. Methods. 100 elderly patients with cerebral aneurysm treated in our hospital from January 2017 to December 2019 were selected, and divided into craniotomy group (40 patients with neurosurgical clipping) and interventional surgery group (60 patients with endovascular interventional embolization) according to the treatment method to compare the operation time, hospitalization time, hospitalization expenses, degree of brain injury, complications and prognostic scores of the patients in two groups. Meanwhile, the relationship between the factors (age, aneurysm size, location) and prognosis of… More >

  • Open Access


    A Patient-Specific Computational Fluid Dynamic Model of Middle Cerebral Artery Aneurysm Before and One Year After Surgery

    Shicheng He1, Juhui Qiu1, Wanling Liu1, Tieying Yin1, Dechuan Zhang2,*, Donghua Liao3,4, Haijun Zhang5, Yuxia Yin5, Guixue Wang1,*

    Molecular & Cellular Biomechanics, Vol.17, No.2, pp. 63-74, 2020, DOI:10.32604/mcb.2020.08750

    Abstract Computational fluid dynamics (CFD) has been widely used for studying intracranial aneurysm hemodynamics, while its use for guiding clinical strategy is still in development. In this study, CFD simulations helped inform treatment decision for a middle cerebral artery (MCA) aneurysm case was investigated. A patient with a 10.4 × 9.8 mm aneurysm attached with a small aneurysm at the edge of the trifurcation in the left MCA was included in this study. For removing the MCA aneurysm, two scenarios were considered: Plan-A involved clipping the small aneurysm and Plan-B involved clipping the whole aneurysm. A suitable treatment plan was decided… More >

  • Open Access


    High-Fidelity Tetrahedral Mesh Generation from Medical Imaging Data for Fluid-Structure Interaction Analysis of Cerebral Aneurysms

    Yongjie Zhang1, Wenyan Wang1, Xinghua Liang1, Yuri Bazilevs2, Ming-Chen Hsu2, Trond Kvamsdal3, Reidar Brekken4, Jørgen Isaksen5

    CMES-Computer Modeling in Engineering & Sciences, Vol.42, No.2, pp. 131-150, 2009, DOI:10.3970/cmes.2009.042.131

    Abstract This paper describes a comprehensive and high-fidelity finite element meshing approach for patient-specific arterial geometries from medical imaging data, with emphasis on cerebral aneurysm configurations. The meshes contain both the blood volume and solid arterial wall, and are compatible at the fluid-solid interface. There are four main stages for this meshing method: 1) Image segmentation and geometric model construction; 2) Tetrahedral mesh generation for the fluid volume using the octree-based method; 3) Mesh quality improvement stage, in which edge-contraction, pillowing, optimization, geometric flow smoothing, and mesh cutting are applied to the fluid mesh; and 4) Mesh generation for the blood… More >

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