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  • Open Access


    Life Threatening Broad QRS Tachycardia in an Infant with Conduction Disorder and SCN5A Mutation

    Elio Caruso1,*, Silvia Farruggio1, Alfredo Di Pino1, Paolo Guccione1, Mohammadrafie Khorgami2

    Congenital Heart Disease, Vol.17, No.5, pp. 551-556, 2022, DOI:10.32604/chd.2022.023711

    Abstract We present the case of an infant admitted to our department for a rapid broad complex tachycardia and cardiovascular collapse. The patient was submitted to genetic testing because of a conduction defect at baseline ECG and family history of gene mutation. A new SCN5A gene mutation variant was found leading to diagnosis of sodium-channel dysfunction arrhythmia. More > Graphic Abstract

    Life Threatening Broad QRS Tachycardia in an Infant with Conduction Disorder and <i>SCN5A</i> Mutation

  • Open Access


    Efficacy and Safety of the Atrial Septal Defect Closure for Patients with Absent or Malaligned Aortic Rim Using a Figulla Flex II Device Flared and Straddling Behind the Aorta

    Masataka Kitano1,2,*, Kazuto Fujimoto1, Atsuko Kato1, Ken-ichi Kurosaki1, Isao Shiraishi1

    Congenital Heart Disease, Vol.16, No.3, pp. 269-283, 2021, DOI:10.32604/CHD.2021.015308

    Abstract Background: Although transcatheter closure of atrial septal defect (ASD) is safe and effective for patients with sufficient rim, ASD patients with absent and/or malaligned aortic and/or superior rim have higher risks of device embolization and cardiac erosion. We have treated such high-risk patients using a Figulla Flex II (FFII) device shaped flared and straddling behind the aorta because this method would avoid such serious complications. However, its long-term efficacy and safety remain unclear. Therefore, the midterm efficacy and safety of this method were studied. Methods: We retrospectively evaluated the outcome of 47 consecutive patients with such rim (age 6–73 years,… More >

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