Qiankun Zuo^1,4, Junhua Hu², Yudong Zhang^3,*, Junren Pan⁴, Changhong Jing⁴, Xuhang Chen⁵, Xiaobo Meng⁶, Jin Hong^7,8,*

CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.3, pp. 2129-2147, 2023, DOI:10.32604/cmes.2023.028732

Abstract The topological connectivity information derived from the brain functional network can bring new insights for diagnosing and analyzing dementia disorders. The brain functional network is suitable to bridge the correlation between abnormal connectivities and dementia disorders. However, it is challenging to access considerable amounts of brain functional network data, which hinders the widespread application of data-driven models in dementia diagnosis. In this study, a novel distribution-regularized adversarial graph auto-Encoder (DAGAE) with transformer is proposed to generate new fake brain functional networks to augment the brain functional network dataset, improving the dementia diagnosis accuracy of data-driven models. Specifically, the label distribution… More > Graphic Abstract

Ashir Javeed^1,2, Ana Luiza Dallora², Johan Sanmartin Berglund^2,*, Arif Ali⁴, Peter Anderberg^2,3, Liaqat Ali⁵

CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 2491-2508, 2023, DOI:10.32604/cmc.2023.033783

Abstract Dementia is a disorder with high societal impact and severe consequences for its patients who suffer from a progressive cognitive decline that leads to increased morbidity, mortality, and disabilities. Since there is a consensus that dementia is a multifactorial disorder, which portrays changes in the brain of the affected individual as early as 15 years before its onset, prediction models that aim at its early detection and risk identification should consider these characteristics. This study aims at presenting a novel method for ten years prediction of dementia using on multifactorial data, which comprised 75 variables. There are two automated diagnostic… More >

Meshal Alharbi, Shabana R. Ziyad^*

CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5483-5505, 2023, DOI:10.32604/cmc.2023.032341

Abstract Aging is a natural process that leads to debility, disease, and dependency. Alzheimer’s disease (AD) causes degeneration of the brain cells leading to cognitive decline and memory loss, as well as dependence on others to fulfill basic daily needs. AD is the major cause of dementia. Computer-aided diagnosis (CADx) tools aid medical practitioners in accurately identifying diseases such as AD in patients. This study aimed to develop a CADx tool for the early detection of AD using the Intelligent Water Drop (IWD) algorithm and the Random Forest (RF) classifier. The IWD algorithm an efficient feature selection method, was used to… More >

Zahid Ullah^1,*, Mona Jamjoom²

CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 1457-1473, 2023, DOI:10.32604/cmc.2023.032752

Abstract Alzheimer’s disease (AD) is a chronic and common form of dementia that mainly affects elderly individuals. The disease is dangerous because it causes damage to brain cells and tissues before the symptoms appear, and there is no medicinal or surgical treatment available yet for AD. AD causes loss of memory and functionality control in multiple degrees according to AD’s progression level. However, early diagnosis of AD can hinder its progression. Brain imaging tools such as magnetic resonance imaging (MRI), computed tomography (CT) scans, positron emission tomography (PET), etc. can help in medical diagnosis of AD. Recently, computer-aided diagnosis (CAD) such… More >