Andrew S. Kim1, Colleen M. Witzenburg2, Mark Conaway3, Jeffrey E. Vergales1, Jeffrey W. Holmes2,4, Thomas J. L’Ecuyer1, Peter N. Dean1
Congenital Heart Disease, Vol.14, No.6, pp. 1185-1192, 2019, DOI:10.1111/chd.12834
Abstract Background: Children with hypoplastic left heart syndrome (HLHS) have risk for
mortality and/or transplantation. Previous studies have associated right ventricular
(RV) indices in a single echocardiogram with survival, but none have related serial
measurements to outcomes. This study sought to determine whether the trajectory
of RV indices in the first year of life was associated with transplant‐free survival to
stage 3 palliation (S3P).
Methods: HLHS patients at a single center who underwent stage 1 palliation (S1P)
between 2000 and 2015 were reviewed. Echocardiographic indices of RV size and
function were obtained before and following S1P and stage 2 palliation (S2P).… More >