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Effectiveness of Maximal Androgen Blockade (MAB): illusion or reality?
Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
Address correspondence to Dr. H. Akaza, Department of
Urology, Institute of Clinical Medicine, University of
Tsukuba, Tsukuba City, Ibaraki, Japan
Canadian Journal of Urology 2005, 12(Suppl.1), 77-80.
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Two decades have passed since the concept of Maximal Androgen Blockade (MAB) was first applied to the clinical treatment of prostate cancer. The theory is that by cutting off the supply of androgen from the adrenal gland, androgen blockade of the prostate could be made more complete. However, to date the clinical benefit of MAB has failed to live up to the theoretically expected effect. Having said that, fundamental research and clinical trials in recent years do indicate that the benefit of MAB is not merely an illusion.Keywords
advanced prostate cancer, hormone therapy, maximal androgen blockade, combined androgen blockade
Cite This Article
APA Style
Akaza, H. (2005). Effectiveness of Maximal Androgen Blockade (MAB): illusion or reality?. Canadian Journal of Urology, 12(Suppl.1), 77–80.
Vancouver Style
Akaza H. Effectiveness of Maximal Androgen Blockade (MAB): illusion or reality?. Can J Urology. 2005;12(Suppl.1):77–80.
IEEE Style
H. Akaza, “Effectiveness of Maximal Androgen Blockade (MAB): illusion or reality?,” Can. J. Urology, vol. 12, no. Suppl.1, pp. 77–80, 2005.
Copyright © 2005 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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