Open Access

CASE REPORT

Malignant pheochromocytoma of the urinary bladder

Daniel Zwahlen, Paula N. Fishman, John Honey, Michael Milosevic, Ian Tannock

Radiation Medicine Program and Department of Medical Oncology and Hematology, Princess Margaret Hospital, Department of Urology, St. Michael’s Hospital and the Departments of Radiation Oncology, Medicine and Urology, University of Toronto, Toronto, Ontario, Canada
Address correspondence to Dr. P. Fishman, Princess Margaret Hospital/University Health Network, 610 University Avenue, Toronto Ontario M5G 2M9 Canada

Canadian Journal of Urology 2007, 14(1), 3455-3457.

Abstract

This report describes an illustrative case of malignant pheochromocytoma of the urinary bladder in a 28-year old man. A combined-modality treatment plan with partial cystectomy and post-operative radiotherapy and concurrent chemotherapy with single agent cisplatin weekly was performed. Three weeks after completing concurrent chemoradiation the first of four planned cycles of cisplatin 25 mg/m² andetoposide 100 mg/m² was administered daily over 3 days. Although there are no controlled series offering proof of benefit, postoperative concurrent chemoradiation followed by chemotherapy alone are reasonable options for patients with residual disease or at high risk for locoregional relapse.

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