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RESIDENT’S CORNER

Nonseminomatous germ cell tumor of the testis 9 years after a germ cell tumor of the pineal gland: case report and review of the literature

Jason Rothman¹, Richard E. Greenberg², William I. Jaffe¹

1 Department of Urology, Temple University Hospital, Philadelphia, Pennsylvania, USA
2 Department of Surgical Oncology, Division of Urology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
Address correspondence to Dr. William I. Jaffe, Department of Urology, Temple University Hospital, 3401 N. Broad Street, 3rd Floor Parkinson Pavilion, Philadelphia, PA 19140 USA

Canadian Journal of Urology 2008, 15(3), 4122-4124.

Abstract

Extragonadal germ cell tumors are extremely rare and account for only 3%-5% of all germ cell tumors. These tumors are rarely associated with metachronous primary testicular germ cell tumors. We report the fourth case of a primary germ cell tumor occurring after the treatment of a primary CNS germ cell tumor in a 27-year-old male with embryonal cell carcinoma of the testicle 9 years after the treatment of a germ cell tumor of the pineal gland. This represents the fi rst case of a non-seminomatous germ cell tumor of the testicle after a CNS germ cell tumor. This case illustrates the importance of long term follow-up and self-examination in patients with extragonadal germ cell tumors.

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