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Synchronous metastatic renal cell carcinoma to the genitourinary tract: two rare case reports and a review of the literature

W. A. Mayer¹, M. J. Resnick¹, D. Canter¹, P. Ramchandani², A. Kutikov¹, J. F. Harryhill¹, V. L. Carpiniello¹, T. J. Guzzo³

1 Division of Urology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
2 Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
3 Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Address correspondence to Dr. Wesley A. Mayer, Division of Urology, University of Pennsylvania School of Medicine, 9 Penn Tower, 34^th and Civic Center Blvd., Philadelphia, PA 19104 USA

Canadian Journal of Urology 2009, 16(2), 4611-4614.

Abstract

Synchronous metastasis of renal cell carcinoma (RCC) to the ureter or the bladder represents an extremely rare event. We report one case of synchronous metastasis of RCC to the ipsilateral ureter and one case of solitary synchronous metastasis of RCC to the urinary bladder. We review the literature and discuss possible mechanisms of dissemination. We discuss the surgical management of metastases from RCC as well as the surgical options in the treatment of these rare occurrences.

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