Open Access

CASE REPORT

Eosinophilic cystitis following immediate post-resection intravesical instillation of mitomycin-C

Jorge Caso¹, Jose Correa¹, Dahui Qin², Wade J. Sexton¹

1 The Genitourinary Oncology Program, H. Lee Moffi tt Cancer Center and Research Institute, Tampa, Florida, USA
2 Department of Anatomic Pathology, H. Lee Moffi tt Cancer Center and Research Institute, Tampa, Florida, USA
Address correspondence to Dr. Wade J. Sexton, Genitourinary Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612-9416 USA

Canadian Journal of Urology 2010, 17(3), 5223-5225.

Abstract

We present a patient who developed severe lower urinary tract symptoms following resection of a Ta low grade bladder urothelial carcinoma with immediate post-resection instillation of mitomycin-C. Urine cultures were negative. Radiographic imaging demonstrated a bladder mass. On biopsy she was found to have eosinophilic cystitis. We report the clinical scenario and discuss treatment options. A review of reported cases in the English literature is provided.

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