Open Access

HOW I DO IT

Intradetrusor onabotulinumtoxinA injection: how I do it

Patrick J. Shenot, J. Ryan Mark

Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Address correspondence to Dr. Patrick J. Shenot, Department of Urology, Thomas Jefferson University, 1025 Walnut Street, Suite 1112, Philadelphia, PA 19107 USA

Canadian Journal of Urology 2013, 20(1), 6649-6655.

Abstract

Overactive bladder is a highly prevalent condition that may have significant impact on quality of life. This condition may be idiopathic or may have a neurogenic etiology. Antimuscarinics have long been the preferred agents for the treatment of this condition. OnabotulinumtoxinA, an injectible agent that prevents presynaptic release of acetylcholine at the neuromuscular junction, has emerged as an important option in the management of patients with urinary incontinence caused by refractory detrusor overactivity. This manuscript describes our technique for performing utilizing this therapy, describes key equipment needed and provides technical tips for avoiding common pitfalls.

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