Open Access

RESIDENT’S CORNER

Acute bilateral ureteral obstruction secondary to guaifenesin toxicity

Patrick A. Cockerill, Mitra R. de Cógáin, Amy E. Krambeck

Department of Urology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Address correspondence to Dr. Amy Krambeck, Department of Urology, Mayo Clinic, 200 1^st Street SW, Rochester, MN 55905 USA

Canadian Journal of Urology 2013, 20(5), 6971-6973.

Abstract

Several medications or their metabolites have been associated with urolithiasis, although overall they remain an infrequent cause of urolithiasis. Guaifenesin stones were originally reported as complexed with ephedrine, and subsequent reports have demonstrated pure guaifenesin stones, occurring after long term abuse. We report a case of a 23-year-old male who ingested a large, one time dose of guaifenesin, resulting in acute bilateral ureteral obstruction, which, to our knowledge, is the frst such reported case in the literature.

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