Open Access

RESIDENT’S CORNER

Primary amyloidosis of the bladder; a mimicker of bladder cancer

Ryan Fitzpatrick¹, Nicholas R. Paterson¹, Eric C. Belanger², Arleigh McCurdy³, James Watterson¹

1 Division of Urology, Department of Surgery, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada
2 Department of Pathology and Laboratory Medicine, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada
3 Division of Hematology, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada
Address correspondence to Dr. James Watterson, The Ottawa Hospital, General Campus, 501 Smyth Road, Box 222, Ottawa, ON K1H 8L6 Canada

Canadian Journal of Urology 2017, 24(3), 8868-8870.

Abstract

Amyloidosis is a protein folding disorder characterized by the deposition of fibrillar proteins into solid organs or tissues. Primary localized amyloidosis of the bladder is very rare and can mimic bladder cancer in its presentation with hematuria, lower urinary tract symptoms or a mass on imaging. A case of localized amyloidosis of the bladder in a 48-year-old man with painless gross hematuria and evidence of bladder mass on ultrasound is presented. Amyloidosis is a rare but important non-malignant process of the bladder. We present a review of the literature and suggestions for management of this rare bladder disease.

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