Open Access

RESIDENT’S CORNER

Blueprint unknown: a case for multidisciplinary management of advanced penile mycosis fungoides

Jonathan S. O’Brien^1,2, Todd Manning^1,2, Marlon Perera^1,2, H. Miles Prince³, Nathan Lawrentschuk^1,2,4,5

1 Department of Surgery, Austin Health, The University of Melbourne, Victoria, Australia
2 Young Urology Researchers Organisation (YURO), Melbourne, Australia
3 Division of Cancer Medicine, Peter MacCallum Cancer Centre and The University of Melbourne, Victoria, Australia
4 Olivia Newton-John Cancer and Wellness Centre, Austin Health, Heidelberg, Victoria, Australia
5 Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Address correspondence to Dr. Nathan Lawrentschuk, 5/210 Burgundy Street, Heidelberg, VIC, 3084

Canadian Journal of Urology 2017, 24(6), 9139-9144.

Abstract

A 64-year-old man presented with a 2 week history of progressive phimosis and painful ulcer on his penile meatus. He underwent penile preserving excision, and subsequent pathological examination confirmed T-cell non-Hodgkin lymphoma with immunohistochemical features of large cell transformation of mycosis fungoides. The penis was further treated with local external beam radiotherapy consisting of 27 Gy in 15 fractions and systemic mini-CHOP chemotherapy. An organ-preserving tissue response has since been achieved. This case is the first of its kind in the literature and firmly highlights the role of multidisciplinary management for this rare malignancy.

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