Open Access

RESIDENT’S CORNER

Secondary mucinous carcinoma of the prostate after low dose rate brachytherapy

Sonja C. Murchison¹, Mildred B. Martens³, Pauline Truong², Abraham Alexander²

1 Department of Radiation Oncology, University of British Columbia, Vancouver, British Columbia, Canada
2 Department of Radiation Oncology, British Columbia Cancer Agency – Vancouver Island Centre, Victoria, British Columbia, Canada
3 Department of Laboratory Medicine and Pathology, Vancouver Island Health Authority, Victoria, British Columbia, Canada
Address correspondence to Dr. Sonja C. Murchison, Department of Radiation Oncology, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4 Canada

Canadian Journal of Urology 2018, 25(2), 9284-9287.

Abstract

Radiation induced malignancy (RIM) after treatment for prostate cancer is well documented after external beam irradiation, but less so in the setting of brachytherapy. We report a case of mucinous adenocarcinoma of the prostate, consistent with a RIM, which developed 12 years after low dose rate brachytherapy for low risk prostate adenocarcinoma. Diagnostic and therapeutic considerations of RIM are discussed. As long term survivors are followed in the community by primary care physicians and urologists, awareness of RIM as a potential late effect of brachytherapy is important to ensure that cases are diagnosed and managed appropriately.

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