Open Access

RESIDENT’S CORNER

Clear cell papillary renal cell carcinoma in a transplant kidney

David Harriman¹, Alexei Mikhailov², Jeffrey Rogers¹, Robert Stratta¹, Alan Farney¹

1 Department of Surgery, Wake Forest, Winston-Salem, North Carolina, USA
2 Department of Pathology, Wake Forest, Winston-Salem, North Carolina, USA
Address correspondence to Dr. David Harriman, Wake Forest, Medical Center Boulevard, Winston-Salem, NC 27157 USA

Canadian Journal of Urology 2019, 26(3), 9794-9798.

Abstract

Large renal cell carcinomas (RCC) arising in allograft kidney transplants are rarely encountered. The distinct RCC sub-type, clear cell papillary RCC (CP-RCC), has mostly been described in non-immunosuppressed patients. Here we report the presentation, management and pathologic diagnosis of a large (11.2 cm, pT2b), multifocal, CP-RCC in a poorly functioning renal allograft of a 63-year-old woman 19 years following kidney transplant. Preoperative angiographic kidney embolization was successfully performed prior to allograft nephrectomy, with an excellent surgical, oncologic and clinical outcome.

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