Open Access

RESIDENT’S CORNER

Bladder squamous cell carcinoma in situ in the background of condyloma acuminatum in a kidney transplant recipient

Crystal Lihong Yan¹, Ryan A. Gallo², Madhavi Pandiri³, Stephen J. Gallo⁴

1 Division of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, Florida, USA
2 University of Miami Miller School of Medicine, Miami, Florida, USA
3 Department of Pathology, University of Massachusetts Chan Medical School Baystate, Springfield, Massachusetts, USA
4 Division of Urology, Department of Surgery, University of Massachusetts Chan Medical School Baystate, Springfield, Massachusetts, USA
Address correspondence to Dr. Crystal Lihong Yan, 1611 NW 12^th Ave, C-600D, Miami, FL 33136 USA

Canadian Journal of Urology 2023, 30(2), 11505-11508.

Abstract

Condyloma acuminatum with synchronous squamous cell carcinoma in situ (CIS) rarely occurs in the bladder. In developed countries, bladder squamous cell carcinoma (SCC) is uncommon. Among the various noninvasive squamous bladder lesions, there is significant morphological overlap, which further complicates accurate diagnosis. Immunosuppression and human papilloma virus increase the risk of bladder condyloma acuminatum, which has a strong association with bladder SCC. Herein, we describe a case of a 79-year-old man with a history of end-stage renal disease with kidney transplantation and anal SCC who presented with bladder squamous cell CIS arising in the background of condyloma acuminatum.

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