Open Access

ARTICLE

Does a prior cancer diagnosis impact PSA testing? Results from the National Health Interview Survey

Alon Lazarovich¹, Thenappan Chandrasekar², Alina Basnet³, Gennady Bratslavsky⁴, Hanan Goldberg⁴

1 Department of Urology, Chaim Sheba Medical Center, Ramat Gan, Israel, affiliated to The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel
2 Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
3 Department of Medical Oncology, SUNY Upstate Medical University, Syracuse, New York, USA
4 Department of Urology, SUNY Upstate Medical University, Syracuse New York, USA
Address correspondence to Dr. Alon Lazarovich, Department of Urology, Sheba Medical Center, 1st Sheba Road, Ramat-Gan, Israel

Canadian Journal of Urology 2023, 30(3), 11551-11557.

Abstract

Introduction: Prostate-specific antigen (PSA) testing remains a controversial issue. However, most urological guidelines recommend PSA testing in men aged 55-69 through a shared decision-making process with the patient. The impact of prior cancer diagnosis on PSA testing is not well-known. To compare PSA testing in men aged 55-69 years with and without a history of cancer (excluding prostate cancer patients).
Materials and methods: Utilizing the National Health Interview Survey (NHIS), a retrospective cross-sectional study during the year 2018 was carried out. Multivariable logistic regression analysis was implemented to demonstrate potential associations with PSA testing and assess the association of cancer history.
Results: A total of 2,892 men aged 55-69 years from the NHIS survey who met the inclusion criteria were analyzed. A total of 308 (10.7%) men had a history of cancer (non-prostate). Men with a cancer history had a higher number of PSA tests and more recent testing than men with no previous cancer history. On multivariable analysis, men who were previously diagnosed with cancer had a higher likelihood of undergoing PSA testing compared to men with no history of cancer (OR: 1.87, 95% CI 1.39-2.52, p < 0.0001).
Conclusions: Our data suggest that men aged 55-69 with a history of cancer are more likely to undergo PSA testing than men with no cancer history.

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