Open Access
REVIEW
Cytokines modulate neutrophil death
1 Centre de Recherche des Cordeliers, Université Pierre et Marie Curie – Paris 6, UMR S 872, Paris; Université Paris-Descartes, UMR S 872, Paris;
Inserm, U872, Paris, France
2 Inserm U955, Faculté Créteil Henri-Mondor, Créteil, France
3 Assistance Publique Hôpitaux de Paris, Hôpital Henri-Mondor, Créteil, France
* Corresponding Author: C. Elbim,
European Cytokine Network 2010, 21(1), 1-6. https://doi.org/10.1684/ecn.2009.0183
Accepted 07 November 2009;
Abstract
Polymorphonuclear neutrophils (PMN) are terminally differentiated cells with a short life span, inthe blood circulation. The prolongation of the life span of PMN is critical in their effectiveness against patho-gens, in particular in the tissues. This review summarizes the effect of cytokines on PMN apoptosis and pointsto some examples of pathological situations characterized by inappropriate cytokine production associated withdysregulation of PMN apoptosis.Keywords
Cite This Article
Copyright © 2010 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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