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ARTICLE
Genipin Cross-linked Boron Doped Hydrogels: Evaluation of Biological Activities
ELIF ANT BURSALI1,*, DILER ABACI1, MURAT KIZIL2, MURUVVET YURDAKOC1
1
Department of Chemistry, Faculty of Sciences, Dokuz Eylul University, Izmir 35390, Turkey.
2 Department of Chemistry, Faculty of Sciences, Dicle University, DiyarbakIr 21280, Turkey
* Corresponding Author: e-mail:
Journal of Polymer Materials 2021, 38(3-4), 231-245. https://doi.org/10.32381/JPM.2021.38.3-4.5
Abstract
Genipin cross-linked/boron doped starch/polyvinily alcohol (PVA) based hydrogel (SH-GNP-B)
was synthesized as a new material having antimicrobial and antioxidant activity. The prepared
hydrogel was characterized by X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy
(FTIR), Thermal Gravimetric Analysis (TGA) and Scanning Electron Microscope (SEM) methods
and evaluated for in vitro antimicrobial activities against selected organisms by disc diffusion
tests. The antioxidant activity of the prepared hydrogels was evaluated using 2,2-diphenyl-1-
picrylhydrazyl radical scavenging assays. Swelling behavior of the hydrogel was also investigated.
The synthesized hydrogel was thermally stable and showed pH independent swelling tendency.
SH-GNP-B hydrogel was found to have antimicrobial activities against Staphylococcus aureus,
Streptecocus pyogenes, Pseudomonas aeruginosa and Bacillus subtilis microorganisms and
antioxidant activities. The antimicrobial activity was improved more effectively by doping boric
acid (B) to hydrogel. The hydrogel exhibited weak antioxidant activity when compared to butylated
hydroxytoluene (BHT).
Keywords
Cite This Article
APA Style
BURSALI, E.A., ABACI, D., KIZIL, M., YURDAKOC, M. (2021). Genipin cross-linked boron doped hydrogels: evaluation of biological activities. Journal of Polymer Materials, 38(3-4), 231-245. https://doi.org/10.32381/JPM.2021.38.3-4.5
Vancouver Style
BURSALI EA, ABACI D, KIZIL M, YURDAKOC M. Genipin cross-linked boron doped hydrogels: evaluation of biological activities. J Polym Materials . 2021;38(3-4):231-245 https://doi.org/10.32381/JPM.2021.38.3-4.5
IEEE Style
E.A. BURSALI, D. ABACI, M. KIZIL, and M. YURDAKOC "Genipin Cross-linked Boron Doped Hydrogels: Evaluation of Biological Activities," J. Polym. Materials , vol. 38, no. 3-4, pp. 231-245. 2021. https://doi.org/10.32381/JPM.2021.38.3-4.5