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  • Open Access

    ARTICLE

    Phytochemical and Pharmacological Study on the Dry Extract of Matricaria discoidea DC. herb and Its Amino Acids Preparations

    Oleh Koshovyi1,2,*, Janne Sepp1, Valdas Jakštas3, Vaidotas Žvikas3, Karina Tolmacheva4, Igor Kireyev4, Jyrki Heinämäki1, Ain Raal1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2909-2925, 2024, DOI:10.32604/phyton.2024.056536 - 30 November 2024

    Abstract Pineappleweed (Matricaria discoidea DC., Asteraceae) herb is an essential oil containing raw material with spasmolytic and anti-inflammatory activity. It is also rich in phenolics, which may be used in pharmaceutical practice. This study aimed to investigate the phenolic and amino acid composition and the hyporific and analgesic effects of the M. discoidea aqueous-ethanolic extract and its amino acid modifications. In addition, we developed a polyethylene oxide gel formulation with M. discoidea extracts for the 3D-printed oral solid dosage preparations. In M. discoidea extracts, 16 phenolic substances and 14 amino acids were established. The extract and its amino acid preparations More >

  • Open Access

    PROCEEDINGS

    Design and Optimization of Microgroove Nreve Guidance Conduits

    Hexin Yue1, Cian Vyas1,2,*, Paulo Bartolo1,2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.011598

    Abstract Peripheral nerve injury can result in significant motor or sensory impairment. Traditional treatments have certain drawbacks and often result in suboptimal clinical results. To overcome these limitations, tissue engineering and bioprinting technologies are promising approaches for manufacturing nerve guidance conduits (NGCs). NGCs are tubular biostructures that bridge the nerve injury site, provide an appropriate microenvironment, and promote peripheral nerve regeneration by guiding axonal growth. The architecture of NGCs needs to mimic the morphology of natural peripheral nerves by designing their topology to regulate nerve cell behaviours. Topographic guidance cues are an effective element in improving… More >

  • Open Access

    PROCEEDINGS

    Developing Two-Wavelength Digital Light Processing-Based Vat Photopolymerization for Multi-Material/High-Resolution 3D Printing

    Xiayun Zhao1,*, Yue Zhang1, Heyang Zhang1, Yousra Bensouda1, Md Jahangir Alam1, Haolin Zhang1, Yiquan Wang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.2, pp. 1-2, 2024, DOI:10.32604/icces.2024.011485

    Abstract Vat photopolymerization (VPP) among other additive manufacturing (AM) processes have a great potential to rapidly print complex 3D components out of a matrix of photo-curable resin. Current VPP processes utilize single-wavelength light exposure, imposing limitations on print speed and throughput, especially in multi-material AM. This is attributed to delays in material switch-over mechanisms. Additionally, the resolution of conventional single-wavelength VPP is constrained by over-curing. Despite ongoing efforts and progress in VPP, there remains a need for effective approaches to address these persistent issues. In this work, we report our development of two-wavelength digital light processing-based… More >

  • Open Access

    PROCEEDINGS

    Three-Dimensionally Printed Transition Metal Catalysts with Hierarchically Porous Structures for Wastewater Purification

    Sheng Guo1,2,*, Mengmeng Yang1, Yao Huang2, Xizi Gao1, Chao Cai3,*, Kun Zhou4,5,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012655

    Abstract 3D printing technology has demonstrated considerable potential in wastewater remediation. Zero-valent metal (ZVM) has been recognized as an efficient catalyst facilitating the organic pollutant degradation in water. However, owing to its inclination toward oxidation and aggregation, the practical utilization of ZVM remains a challenge. Herein, we have employed 3D printing techniques to fabricate hierarchically porous ZVM, such as zero-valent copper and zero-valent iron, which exhibit a high level of printing precision and commendable resistance to compression. These 3D-ZVM catalysts can effectively activate peroxymonosulfate (PMS), thereby degrading various organic pollutants, including tetracycline, ciprofloxacin, rhodamine B, and… More >

  • Open Access

    PROCEEDINGS

    Miura-Origami Soft Robots with Proprioceptive and Interactive Sensing via Embedded Optical Sensors

    Shaowu Tang1, Sicong Liu1,*, Jian S Dai1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.3, pp. 1-1, 2024, DOI:10.32604/icces.2024.011746

    Abstract Origami, a traditional and elegant folding technique, provides a solution for the deformation of three-dimensional structures. Inspired by this, origami-based soft actuators and robots exhibit the advantages of portability, high efficiency, and programmability when performing functions such as locomotion, manipulation, and interaction. However, these deformable origami structures bring challenges to sensing methods and technologies, due to hyperelastic deformations of the soft materials. In this work, a sensing approach is proposed to enable origami robots with proprioceptive and interactive sensing capabilities. The 3D-printed Miura-ori chambers of the robot are embedded with infrared optical sensors (a light-emitting… More >

  • Open Access

    PROCEEDINGS

    Subdivisional Modelling Method for Matched Metal Additive Manufacturing and Its Implementation on Novel Negative Poisson's Ratio Lattice Structures

    Ruiqi Pan1, Wei Xiong2, Liang Hao1,*, Yan Li1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.011651

    Abstract As metal additive manufacturing (MAM) becomes more widely used in engineering, an increasing number of novel lattice structures are being developed. However, most recently developed lattice structures do not match the requirement of MAM efficiently. Based on the Design for Additive Manufacturing (DfAM), comparing the mainstream implicit and explicit modelling methods, it is proposed to introduce a Subdivisional (Sub-D) modelling method to model lattice structures with better modelling versatility, 3D printability, and mechanical properties. To this end, a novel negative Poisson's ratio (NPR) structure is developed as an example to demonstrate the efficient and wide… More >

  • Open Access

    ARTICLE

    Research on the Microstructure Construction Technology of Fully Degraded Polymer Vascular Stent Based on Electric Field Driven 3D Printing

    Yanpu Chao1,*, Fulai Cao1, Hao Yi2,3,*, Shuai Lu1, Yaohui Li1, Hui Cen1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.11, pp. 2489-2508, 2024, DOI:10.32604/fdmp.2024.051962 - 28 October 2024

    Abstract The so-called fourth-generation biodegradable vascular stent has become a research hotspot in the field of bio-engineering because of its good degradation ability and drug-loading characteristics. However, the preparation of polymer-degraded vascular stents is affected by known problem such as poor process flexibility, low forming accuracy, large diameter wall thickness, limited complex pore structure, weak mechanical properties of radial support and high process cost. In this study, a deposition technique based on a high-voltage electric-field-driven continuous rotating jet is proposed to fabricate fully degraded polymer vascular stents. The experimental results show that, due to the rotation… More > Graphic Abstract

    Research on the Microstructure Construction Technology of Fully Degraded Polymer Vascular Stent Based on Electric Field Driven 3D Printing

  • Open Access

    PROCEEDINGS

    3D Printing of Overhanging Microstructures for Tunable Liquid Wettability

    Xiaojiang Liu1,*, Zhongze Gu1, Kun Zhou2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.3, pp. 1-2, 2024, DOI:10.32604/icces.2024.011320

    Abstract Surfaces with overhanging microstructures play an essential role in surface wettability. Typically, surfaces with tightly-distributed multiply symmetric re-entrant microstructures enable the liquid suspension toward water, oil, and even n-perfluorooctane, whose surface tension is as low as 12.0 mN/m [1-4]. In contrast, surfaces with asymmetric re-entrant microstructures are favorable for unidirectional liquid spreading, where the liquids exhibit a small contact angle on the surfaces [5]. These fantastic wettability behaviors can be attributed to three-dimensional (3D) features of the overhanging microstructures, where the edge effect and Laplace pressure difference are generated on the overhanging microstructures. Based on… More >

  • Open Access

    PROCEEDINGS

    3D Printing of Electrically Conductive and Degradable Hydrogel for Epidermal Strain Sensor

    Binbin Guo1,2, Hui Ying Yang1,*, Jiaming Bai2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012673

    Abstract Due to excellent electrical conductivity, stretchability, and biocompatibility, electrically conductive hydrogels have been widely used in flexible wearable strain sensors. Generally, conductive fillers need to be integrated with the hydrogel matrix to impart electrical conductivity. According to the method of composite formation between electronic conductive fillers and hydrogel matrix, conductive hydrogels can be classified into embedded conductive and coated conductive hydrogels. Additionally, due to the intrinsic chemical and physical crosslinking networks, traditional hydrogels are not degradable, resulting in severe environmental pollution problems. Herein, we designed electrically conductive and degradable hydrogels for the epidermal strain sensor… More >

  • Open Access

    PROCEEDINGS

    The Staggered Design of Multi-Diaphragm in Thin-Walled Structures for Improving Compressive Performance

    Qianbing Tan1,*, Jin Wang1, Yisen Liu1, Guangyu Sun1, Huijing Gao1, Yong Peng1, Song Yao1, Kui Wang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.011212

    Abstract Bio-inspired thin-walled structures have attracted widespread attention in the engineering field due to their excellent energy absorption capacity. In this work, it was observed that the stem of the bird-of-paradise plant consisted of longitudinal thin walls and transverse diaphragms. The diaphragms inside of the stems are parallel to each other within a column and exhibit staggered arrangements in the adjacent columns. Inspired by the stem of the bird-of-paradise plant, the staggered diaphragm design was introduced to improve the compressive properties of structures. Considering the staggered arrangement method and the Centro symmetry method, three types of… More >

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