Abdullah A. Asiri¹, Toufique A. Soomro^2,3,*, Ahmed Ali⁴, Faisal Bin Ubaid⁵, Muhammad Irfan^6,*, Khlood M. Mehdar⁷, Magbool Alelyani⁸, Mohammed S. Alshuhri⁹, Ahmad Joman Alghamdi¹⁰, Sultan Alamri¹⁰

CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.1, pp. 255-287, 2025, DOI:10.32604/cmes.2025.061683 - 11 April 2025

Abstract Global mortality rates are greatly impacted by malignancies of the brain and nervous system. Although, Magnetic Resonance Imaging (MRI) plays a pivotal role in detecting brain tumors; however, manual assessment is time-consuming and susceptible to human error. To address this, we introduce ICA2-SVM, an advanced computational framework integrating Independent Component Analysis Architecture-2 (ICA2) and Support Vector Machine (SVM) for automated tumor segmentation and classification. ICA2 is utilized for image preprocessing and optimization, enhancing MRI consistency and contrast. The Fast-Marching Method (FMM) is employed to delineate tumor regions, followed by SVM for precise classification. Validation on More >

Zhiyong Li, Xinlian Zhou^*

CMC-Computers, Materials & Continua, Vol.83, No.1, pp. 739-760, 2025, DOI:10.32604/cmc.2025.059807 - 26 March 2025

Abstract Brain tumor classification is crucial for personalized treatment planning. Although deep learning-based Artificial Intelligence (AI) models can automatically analyze tumor images, fine details of small tumor regions may be overlooked during global feature extraction. Therefore, we propose a brain tumor Magnetic Resonance Imaging (MRI) classification model based on a global-local parallel dual-branch structure. The global branch employs ResNet50 with a Multi-Head Self-Attention (MHSA) to capture global contextual information from whole brain images, while the local branch utilizes VGG16 to extract fine-grained features from segmented brain tumor regions. The features from both branches are processed through More >

Tawfeeq Shawly¹, Ahmed A. Alsheikhy^2,*

CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4161-4179, 2025, DOI:10.32604/cmc.2025.061497 - 06 March 2025

Abstract A healthy brain is vital to every person since the brain controls every movement and emotion. Sometimes, some brain cells grow unexpectedly to be uncontrollable and cancerous. These cancerous cells are called brain tumors. For diagnosed patients, their lives depend mainly on the early diagnosis of these tumors to provide suitable treatment plans. Nowadays, Physicians and radiologists rely on Magnetic Resonance Imaging (MRI) pictures for their clinical evaluations of brain tumors. These evaluations are time-consuming, expensive, and require expertise with high skills to provide an accurate diagnosis. Scholars and industrials have recently partnered to implement… More >

Gaoshuai Su^1,2, Hongyang Li^1,*, Huafeng Chen^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.3, pp. 2527-2545, 2025, DOI:10.32604/cmes.2025.059452 - 03 March 2025

Abstract Brain tumors, one of the most lethal diseases with low survival rates, require early detection and accurate diagnosis to enable effective treatment planning. While deep learning architectures, particularly Convolutional Neural Networks (CNNs), have shown significant performance improvements over traditional methods, they struggle to capture the subtle pathological variations between different brain tumor types. Recent attention-based models have attempted to address this by focusing on global features, but they come with high computational costs. To address these challenges, this paper introduces a novel parallel architecture, ParMamba, which uniquely integrates Convolutional Attention Patch Embedding (CAPE) and the… More >

Khalid Jamil¹, Wahab Khan¹, Bilal Khan², Sarwar Shah Khan^2,*

Digital Engineering and Digital Twin, Vol.3, pp. 1-16, 2025, DOI:10.32604/dedt.2025.058943 - 28 February 2025

Abstract Brain tumors are one of the deadliest cancers, partly because they’re often difficult to detect early or with precision. Standard Magnetic Resonance Imaging (MRI) imaging, though essential, has limitations, it can miss subtle or early-stage tumors, which delays diagnosis and affects patient outcomes. This study aims to tackle these challenges by exploring how machine learning (ML) can improve the accuracy of brain tumor identification from MRI scans. Motivated by the potential for artificial intillegence (AI) to boost diagnostic accuracy where traditional methods fall short, we tested several ML models, with a focus on the K-Nearest More >

Xuemei Yang¹, Yuting Zhou², Shiqi Liu¹, Junping Yin^2,3,*

CMC-Computers, Materials & Continua, Vol.82, No.2, pp. 3281-3307, 2025, DOI:10.32604/cmc.2024.057991 - 17 February 2025

Abstract Aiming at the problems of information loss and the relationship between features and target tasks in multimodal medical image segmentation, a multimodal medical image segmentation algorithm based on feature decoupling and information bottleneck theory is proposed in this paper. Based on the reversible network, the bottom-up learning method for different modal information is constructed, which enhances the features’ expression ability and the network’s learning ability. The feature fusion module is designed to balance multi-directional information flow. To retain the information relevant to the target task to the maximum extent and suppress the information irrelevant to… More >

Mudassir Khalil¹, Muhammad Imran Sharif^2,*, Ahmed Naeem³, Muhammad Umar Chaudhry¹, Hafiz Tayyab Rauf^4,*, Adham E. Ragab⁵

CMC-Computers, Materials & Continua, Vol.82, No.1, pp. 1461-1461, 2025, DOI:10.32604/cmc.2024.061589 - 03 January 2025

Abstract This article has no abstract. More >

SOROUSH SOLEYMANI¹, MOHAMMAD DOROUDIAN^2,*, MAHDIEH SOEZI^3,4, ALI BELADI⁵, KIARASH ASGARI², ASO MOBARAKSHAHI², ARYANA AGHAEIPOUR², RONAN MACLOUGHLIN^6,7,8,*

Oncology Research, Vol.33, No.1, pp. 15-26, 2025, DOI:10.32604/or.2024.053069 - 20 December 2024

Abstract Brain metastasis and primary glioblastoma multiforme represent the most common and lethal malignant brain tumors. Its median survival time is typically less than a year after diagnosis. One of the major challenges in treating these cancers is the efficiency of the transport of drugs to the central nervous system. The blood-brain barrier is cooperating with advanced stages of malignancy. The blood-brain barrier poses a significant challenge to delivering systemic medications to brain tumors. Nanodrug delivery systems have emerged as promising tools for effectively crossing this barrier. Additionally, the development of smart nanoparticles brings new hope More >

ZAREMA GILAZIEVA¹, DANIIL MOLDAVSKII¹, EKATERINA LUZINA¹, AISYLU KADYROVA¹, ALISA SHAIMARDANOVA¹, SHAZA ISSA², ALBERT RIZVANOV^1,3,*, VALERIYA SOLOVYEVA¹

BIOCELL, Vol.48, No.12, pp. 1667-1681, 2024, DOI:10.32604/biocell.2024.058490 - 30 December 2024

Abstract Aggressive malignant brain tumors have a poor prognosis, and early detection can significantly improve treatment effectiveness and increase patient survival rates. Various methods are available for diagnosing brain tumors, with biopsy being one of the primary options. However, a biopsy is an invasive procedure that carries a risk of brain damage, highlighting the need for safer alternatives. One promising non-invasive method is liquid biopsy, which involves extracting extracellular vesicles (EVs) from different biological fluids. Most cell types can produce and release extracellular vesicles. EVs isolated from bodily fluids, along with the molecules they carry—such More >

Mahesh Thyluru Ramakrishna¹, Kuppusamy Pothanaicker², Padma Selvaraj³, Surbhi Bhatia Khan^4,7,*, Vinoth Kumar Venkatesan⁵, Saeed Alzahrani⁶, Mohammad Alojail⁶

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 867-883, 2024, DOI:10.32604/cmc.2024.053563 - 15 October 2024

Abstract Brain tumor is a global issue due to which several people suffer, and its early diagnosis can help in the treatment in a more efficient manner. Identifying different types of brain tumors, including gliomas, meningiomas, pituitary tumors, as well as confirming the absence of tumors, poses a significant challenge using MRI images. Current approaches predominantly rely on traditional machine learning and basic deep learning methods for image classification. These methods often rely on manual feature extraction and basic convolutional neural networks (CNNs). The limitations include inadequate accuracy, poor generalization of new data, and limited ability… More >