Haohan Zhao¹, Xingchen Zhu², Wencan Li^3,*, Xin Lin^4,*

International Journal of Mental Health Promotion, Vol.27, No.4, pp. 517-540, 2025, DOI:10.32604/ijmhp.2025.062739 - 30 April 2025

Abstract Background: Despite increasing attention to parental educational anxiety in China’s educational system, the underlying mechanisms through which this anxiety affects adolescent academic performance remain unclear. This study aims to investigate how parental educational anxiety influences academic outcomes through depression and self-efficacy while considering the role of problematic social media use in today’s digital age. Methods: Data analysis was conducted using stratified random cluster sampling techniques. Participants for this study were recruited from middle and high schools in China. The sample comprised 2579 traditional two-parent families, each consisting of a pair of parents and one child.… More >

Agar Marín-Morales^1,2,*, Sofia Amaoui², Carmen Fernández-Fillol^2,3,4, Gustavo Carlo⁵, Sandra Rivas-García^2,6

International Journal of Mental Health Promotion, Vol.27, No.4, pp. 561-576, 2025, DOI:10.32604/ijmhp.2025.058881 - 30 April 2025

Abstract Background: Prosocial behavior plays a crucial role in improving interpersonal relationships and social well-being, especially in times of crisis. The COVID-19 pandemic caused a severe humanitarian crisis, prompting governments to implement measures such as social confinement. The main objective of the study was to analyze the psychological and sociodemographic variables that may predict prosocial behavior during quarantine. Methods: The sample consisted of 172 participants from Spain, divided into two groups based on whether they reported an increase in prosocial behaviors during quarantine. An online survey was administered to analyze the psychological and sociodemographic variables. Results: Overall, More >

Ridha Djebali^1,*, Bernard Pateyron², Mokhtar Ferhi¹, Mohamed Ouerhani³, Karim Khemiri¹, Montassar Najari¹, M. Ammar Abbassi⁴, Chohdi Amri⁵, Ridha Ennetta⁶, Zied Driss⁷

Frontiers in Heat and Mass Transfer, Vol.23, No.2, pp. 441-461, 2025, DOI:10.32604/fhmt.2025.063375 - 25 April 2025

Abstract This paper investigates the application of Direct Current Atmospheric Plasma Spraying (DC-APS) as a versatile thermal spray technique for the application of coatings with tailored properties to various substrates. The process uses a high-speed, high-temperature plasma jet to melt and propel the feedstock powder particles, making it particularly useful for improving the performance and durability of components in renewable energy systems such as solar cells, wind turbines, and fuel cells. The integration of nanostructured alumina (Al₂O₃) thin films into multilayer coatings is considered a promising advancement that improves mechanical strength, thermal stability, and environmental resistance. The More >

Oncology Research Editorial Office

Oncology Research, Vol.33, No.5, pp. 1251-1252, 2025, DOI:10.32604/or.2025.065346 - 18 April 2025

Abstract This article has no abstract. More >

JINGDAN QUAN¹, ZIXIN WAN¹, WEI WU², XINYUAN CAO², JIAYUAN QIU², XIAOYE LIU², ZHIWEI ZHANG^1,*

Oncology Research, Vol.33, No.5, pp. 1069-1089, 2025, DOI:10.32604/or.2025.063005 - 18 April 2025

Abstract One of the most prevalent malignant tumors worldwide, stomach cancer still has a high incidence and fatality rate in China, and the number of young people developing early-onset gastric cancer is steadily increasing. The 5-year survival rate of stomach cancer is typically 30%–35%, the prognosis is bad, the patients’ quality of life is low, and the progression of advanced gastric cancer cannot be effectively managed despite the use of surgical surgery, chemotherapy, and other medicines. We urgently need molecular biomarkers with high specificity and sensitivity to increase the early gastric cancer detection rate, extend patient… More >

YU QIU^1,#, RUIHAN LIU^2,#, SHANSHAN HUANG¹, QIAOTING CAI¹, YI XIE¹, ZHITING HE¹, WEIGE TAN^2,*, XINHUA XIE^1,*

Oncology Research, Vol.33, No.5, pp. 1135-1147, 2025, DOI:10.32604/or.2025.062767 - 18 April 2025

Abstract Objectives: Deubiquitinase OTUB2 plays a critical role in the progression of various tumors. However, its specific role in triple-negative breast cancer (TNBC) remains unclear. This study aims to elucidate the biological function of OTUB2 in TNBC and uncover the underlying mechanisms. Methods: First, we found that the expression of OTUB2 was upregulated in TNBC by bioinformatics analysis, we then validated its expression in TNBC tissues and cells using immunohistochemistry (IHC) and qPCR and plotted the survival curves by Kaplan-Meier method. Gene set enrichment analysis (GSEA) suggested that OTUB2 may be involved in tumor proliferation and metastasis.… More > Graphic Abstract

XI ZHU^1,2,#, KAI HUANG^3,#, XIAOMING KAO², ZHAOHUI TANG³, WENJIE GUO³, TIANCONG WU^4,*, QIURONG LI^1,2,*

Oncology Research, Vol.33, No.5, pp. 1149-1159, 2025, DOI:10.32604/or.2024.054930 - 18 April 2025

Abstract Background: Colorectal cancer (CRC) holds the third position in global cancer prevalence mortality. Although chemotherapy is a conventional treatment, recent investigations have shed light on the therapeutic potential of the cGAS cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway in CRC management. Despite the primary role of the death domain-associated protein (Daxx) in cellular apoptosis, its influence on the regulation of cGAS-STING activation remains elusive. Methods: The Daxx degradation and speck formation were conducted using immunofluorescence and Western blotting. The Daxx knock-down and over-expression in CRC cells were performed to detect in vivo and in vitro… More >

LIWEN FENG^1,2,#,*, YUTING CHEN^3,#, WENYI JIN⁴

Oncology Research, Vol.33, No.5, pp. 1091-1103, 2025, DOI:10.32604/or.2024.054207 - 18 April 2025

Abstract Osteosarcoma (OS) is a prevalent primary bone malignancy with limited treatment options. Therefore, it is imperative to investigate and understand the mechanisms underlying OS pathogenesis. Cancer-associated fibroblasts (CAFs) are markedly abundant in tumor stromal cells and are essentially involved in the modulation of tumor occurrence and development. In recent years, CAFs have become a hotspot as researchers aim to elucidate CAF mechanisms that regulate tumor progression. However, most studies on CAFs are limited to a few common cancers, and their association with OS remains elusive. This review describes the role and current knowledge of CAFs More >

Federica Uccello^1,2, Marek Pawlicki^3,4, Salvatore D'Antonio¹, Rafał Kozik^3,4, Michał Choraś^3,4,*

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1607-1621, 2025, DOI:10.32604/cmc.2025.062801 - 16 April 2025

Abstract The growing sophistication of cyberthreats, among others the Distributed Denial of Service attacks, has exposed limitations in traditional rule-based Security Information and Event Management systems. While machine learning–based intrusion detection systems can capture complex network behaviours, their “black-box” nature often limits trust and actionable insight for security operators. This study introduces a novel approach that integrates Explainable Artificial Intelligence—xAI—with the Random Forest classifier to derive human-interpretable rules, thereby enhancing the detection of Distributed Denial of Service (DDoS) attacks. The proposed framework combines traditional static rule formulation with advanced xAI techniques—SHapley Additive exPlanations and Scoped Rules More >

Yahya Tashtoush^1,*, Areen Banysalim¹, Majdi Maabreh², Shorouq Al-Eidi³, Ola Karajeh⁴, Plamen Zahariev⁵

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 3113-3134, 2025, DOI:10.32604/cmc.2025.062724 - 16 April 2025

Abstract Social media has emerged as one of the most transformative developments on the internet, revolutionizing the way people communicate and interact. However, alongside its benefits, social media has also given rise to significant challenges, one of the most pressing being cyberbullying. This issue has become a major concern in modern society, particularly due to its profound negative impacts on the mental health and well-being of its victims. In the Arab world, where social media usage is exceptionally high, cyberbullying has become increasingly prevalent, necessitating urgent attention. Early detection of harmful online behavior is critical to… More >