RUCHI SHAH1,*, SONALI VERMA1, AMRITA BHAT1, GH RASOOL BHAT1, VARUN SHARMA1, INDU SHARMA1, HEMENDER SINGH1, SANDEEP KAUL2, EKTA RAI1, SWARKAR SHARMA1,*
BIOCELL, Vol.45, No.3, pp. 665-670, 2021, DOI:10.32604/biocell.2021.09629
Abstract Esophageal cancer is the second most common type of cancer after lung carcinoma in the state of Jammu and
Kashmir (J&K). The understanding of genetics in Esophageal cancer development is poor in the state. Genome wide
association studies (GWAS) has proved to be unsurpassed tool in identification of new loci associated with different
cancers. GWAS in Chinese population has identified SNP rs2294693 present in UNC5CL (UNC-5 Family C-Terminal
like) to be associated with non-cardia gastric cancer. We performed a case control association study and genotyped
the SNP rs2294693 using Taqman allele discrimination assay in 566 individuals (166 esophageal cancer patients… More >
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