Sara Tehsin1, Inzamam Mashood Nasir1,*, Wiem Abdelbaki2, Fadwa Alrowais3, Khalid A. Alattas4, Sultan Almutairi5, Radwa Marzouk6
CMC-Computers, Materials & Continua, Vol.87, No.1, 2026, DOI:10.32604/cmc.2025.074416
- 10 February 2026
Abstract Objective: Deep learning is employed increasingly in Gastroenterology (GI) endoscopy computer-aided diagnostics for polyp segmentation and multi-class disease detection. In the real world, implementation requires high accuracy, therapeutically relevant explanations, strong calibration, domain generalization, and efficiency. Current Convolutional Neural Network (CNN) and transformer models compromise border precision and global context, generate attention maps that fail to align with expert reasoning, deteriorate during cross-center changes, and exhibit inadequate calibration, hence diminishing clinical trust. Methods: HMA-DER is a hierarchical multi-attention architecture that uses dilation-enhanced residual blocks and an explainability-aware Cognitive Alignment Score (CAS) regularizer to directly align… More >