Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (867)
  • Open Access

    ARTICLE

    A Temperature-Indexed Concrete Damage Plasticity Model Incorporating Bond-Slip Mechanism for Thermo-Mechanical Analysis of Reinforced Concrete Structures

    Wu Feng1,2,*, Tengku Anita Raja Hussin1, Xu Yang3

    Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.071664 - 08 January 2026

    Abstract This study investigates the thermo–mechanical behavior of C40 concrete and reinforced concrete subjected to elevated temperatures up to 700°C by integrating experimental testing and advanced numerical modeling. A temperature-indexed Concrete Damage Plasticity (CDP) framework incorporating bond–slip effects was developed in Abaqus to capture both global stress–strain responses and localized damage evolution. Uniaxial compression tests on thermally exposed cylinders provided residual strength data and failure observations for model calibration and validation. Results demonstrated a distinct two-stage degradation regime: moderate stiffness and strength reduction up to ~400°C, followed by sharp deterioration beyond 500°C–600°C, with residual capacity at… More >

  • Open Access

    ARTICLE

    H/V Spectral Ratio Reveals Seismic Response of Base-Isolated Large-Span High-Rise in Beijing

    Zhangdi Xie1,2,*, Cantao Zhuang1, Yong Wu1, Linghui Niu1, Jianming Zhao3

    Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.070531 - 08 January 2026

    Abstract This study employed tri-component continuous monitoring data from 10 measurement points on both sides of a base isolation layer in the basement of a large-span high-rise building in Beijing, as well as from a free-field station and roof frame, during a Mw 5.5 magnitude earthquake in Pingyuan, Shandong, in 2023. The H/V spectral ratio method was used to evaluate the structural dynamic response characteristics of the building and analyze the regulatory effect of the base-isolation layer on seismic waves. The results indicate that during the earthquake, the peak frequency of the free-field and the measurement points… More >

  • Open Access

    REVIEW

    Branched-Chain Amino Acid Metabolic Reprogramming and Cancer: Molecular Mechanisms, Immune Regulation, and Precision Targeting

    Dongchi Cai1,2,#, Jialin Ji3,#, Chunhui Yang1,*, Hong Cai1,*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.071152 - 30 December 2025

    Abstract Metabolic reprogramming involving branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—is increasingly recognized as pivotal in cancer progression, metastasis, and immune modulation. This review comprehensively explores how cancer cells rewire BCAA metabolism to enhance proliferation, survival, and therapy resistance. Tumors manipulate BCAA uptake and catabolism via high expression of transporters like L-type amino acid transporter 1 (LAT1) and enzymes including branched chain amino acid transaminase 1(BCAT1), branched chain amino acid transaminase 2 (BCAT2), branched-chain alpha-keto acid dehydrogenase (BCKDH), and branched chain alpha-keto acid dehydrogenase kinase (BCKDK). These alterations sustain energy production, biosynthesis, redox homeostasis, and oncogenic… More >

  • Open Access

    REVIEW

    The Role of Exosomes as a Key Factor of Cytostatic Resistance in Cancer: Mechanisms of Action, Potential Biomarkers, and Possible Exosome-Based Therapies

    Sandra Kałużna1,*, Monika Świerczewska1,2, Sylwia Ciesiółka1, Małgorzata Partyka1, Michał Nowicki1, Karolina Wojtowicz1

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070356 - 30 December 2025

    Abstract The last research focuses on the role of exosomes in cancer treatment. Exosomes are extracellular vesicles. They can be secreted by cancer cells, and they can modulate chemotherapy sensitivity. Determining exosomal content opens the possibility for guiding treatment strategies for cancer diseases. Exosomal microRNA are considered one of the prime candidates for exosomal biomarkers. Exosomal circular RNAs represent excellent biomarkers for liquid biopsy because of their stability in many types of cancer. Exosomal proteins remain reliable biomarkers also. Exosomes have emerged as promising therapeutic candidates. Their biological properties render them ideal vectors for drug delivery.… More >

  • Open Access

    REVIEW

    Ferroptosis: Mechanisms, Comparison with Cuproptosis and Emerging Horizons in Therapeutics

    Shujie Yin1, Zong Li1, Wen-Bin Ou1,2,*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069049 - 30 December 2025

    Abstract Ferroptosis is an iron-dependent, excessive lipid peroxidation-driven form of regulated cell death. The core mechanisms of ferroptosis include lipid peroxidation cascade, System Xc-glutathioneglutathione peroxidase 4 axis, iron and lipid metabolism chaos, the NAD(P)Hferroptosis suppressor protein 1—ubiquinone axis, and GTP cyclohydrolase 1 tetrahydrobiopterin-dihydrofolate reductase axis. Cuproptosis is triggered by copper ions and involves ferredoxin 1-mediated aggregation of lipoylated proteins, differing fundamentally from ferroptosis. Both ferroptosis and cuproptosis exhibit dual roles (promote or inhibit) in cancers. And the sensitivity of different cancer types to ferroptosis varies, which may depend on special metabolic signatures (e.g., E-cadherin loss causes epithelial–mesenchymal More > Graphic Abstract

    Ferroptosis: Mechanisms, Comparison with Cuproptosis and Emerging Horizons in Therapeutics

  • Open Access

    REVIEW

    Male Breast Cancer: Epidemiology, Diagnosis, Molecular Mechanisms, Therapeutics, and Future Prospective

    Ashok Kumar Sah1,*, Ranjay Kumar Choudhary1,2, Velilyaeva Alie Sabrievna3, Karomatov Inomdzhon Dzhuraevich4, Anass M. Abbas5, Manar G. Shalabi5, Nadeem Ahmad Siddique6, Raji Rubayyi Alshammari7, Navjyot Trivedi8, Rabab H. Elshaikh1

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068238 - 30 December 2025

    Abstract Male breast cancer (MBC) is rare, representing 0.5%–1% of all breast cancers, but its incidence is increasing due to improved diagnostics and awareness. MBC typically presents in older men, is human epidermal growth factor receptor 2 (HER2)-negative and estrogen receptor (ER)-positive, and lacks routine screening, leading to delayed diagnosis and advanced disease. Major risk factors include hormonal imbalance, radiation exposure, obesity, alcohol use, and Breast Cancer Gene 1 and 2 (BRCA1/2) mutations. Clinically, it may resemble gynecomastia but usually appears as a unilateral, painless mass or nipple discharge. Advances in imaging and liquid biopsy have More >

  • Open Access

    ARTICLE

    A Hierarchical Attention Framework for Business Information Systems: Theoretical Foundation and Proof-of-Concept Implementation

    Sabina-Cristiana Necula*, Napoleon-Alexandru Sireteanu

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-34, 2026, DOI:10.32604/cmc.2025.070861 - 09 December 2025

    Abstract Modern business information systems face significant challenges in managing heterogeneous data sources, integrating disparate systems, and providing real-time decision support in complex enterprise environments. Contemporary enterprises typically operate 200+ interconnected systems, with research indicating that 52% of organizations manage three or more enterprise content management systems, creating information silos that reduce operational efficiency by up to 35%. While attention mechanisms have demonstrated remarkable success in natural language processing and computer vision, their systematic application to business information systems remains largely unexplored. This paper presents the theoretical foundation for a Hierarchical Attention-Based Business Information System (HABIS)… More >

  • Open Access

    ARTICLE

    PMCFusion: A Parallel Multi-Dimensional Complementary Network for Infrared and Visible Image Fusion

    Xu Tao1, Qiang Xiao2, Zhaoqi Jin2, Hao Li1,*

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-18, 2026, DOI:10.32604/cmc.2025.070790 - 09 December 2025

    Abstract Image fusion technology aims to generate a more informative single image by integrating complementary information from multi-modal images. Despite the significant progress of deep learning-based fusion methods, existing algorithms are often limited to single or dual-dimensional feature interactions, thus struggling to fully exploit the profound complementarity between multi-modal images. To address this, this paper proposes a parallel multi-dimensional complementary fusion network, termed PMCFusion, for the task of infrared and visible image fusion. The core of this method is its unique parallel three-branch fusion module, PTFM, which pioneers the parallel synergistic perception and efficient integration of… More >

  • Open Access

    ARTICLE

    Dynamic Knowledge Graph Reasoning Based on Distributed Representation Learning

    Qiuru Fu1, Shumao Zhang1, Shuang Zhou1, Jie Xu1,*, Changming Zhao2, Shanchao Li3, Du Xu1,*

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.070493 - 09 December 2025

    Abstract Knowledge graphs often suffer from sparsity and incompleteness. Knowledge graph reasoning is an effective way to address these issues. Unlike static knowledge graph reasoning, which is invariant over time, dynamic knowledge graph reasoning is more challenging due to its temporal nature. In essence, within each time step in a dynamic knowledge graph, there exists structural dependencies among entities and relations, whereas between adjacent time steps, there exists temporal continuity. Based on these structural and temporal characteristics, we propose a model named “DKGR-DR” to learn distributed representations of entities and relations by combining recurrent neural networks More >

  • Open Access

    ARTICLE

    An Attention-Based 6D Pose Estimation Network for Weakly Textured Industrial Parts

    Song Xu1,2,*, Liang Xuan1,2, Yifeng Li1,2, Qiang Zhang1,2

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.070472 - 09 December 2025

    Abstract The 6D pose estimation of objects is of great significance for the intelligent assembly and sorting of industrial parts. In the industrial robot production scenarios, the 6D pose estimation of industrial parts mainly faces two challenges: one is the loss of information and interference caused by occlusion and stacking in the sorting scenario, the other is the difficulty of feature extraction due to the weak texture of industrial parts. To address the above problems, this paper proposes an attention-based pixel-level voting network for 6D pose estimation of weakly textured industrial parts, namely CB-PVNet. On the… More >

Displaying 1-10 on page 1 of 867. Per Page