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  • Open Access

    ARTICLE

    Elaboration of Materials with Functionality Gradients by Assembly of Chitosan-Collagen Microspheres Produced by Microfluidics

    David Azria1,2, Raluca Guermache1,2, Sophie Raisin1, Sébastien Blanquer1, Frédéric Gobeaux3, Marie Morille1, Emmanuel Belamie1,2,*

    Journal of Renewable Materials, Vol.6, No.3, pp. 314-324, 2018, DOI:10.7569/JRM.2017.634186

    Abstract Biopolymers extracted from renewable resources like chitosan and collagen exhibit interesting properties for the elaboration of materials designed for tissue engineering applications, among which are their hydrophilicity, biocompatibility and biodegradability. In many cases, functional recovery of an injured tissue or organ requires oriented cell outgrowth, which is particularly critical for nerve regeneration. Therefore, there is a growing interest for the elaboration of materials exhibiting functionalization gradients able to guide cells. Here, we explore an original way of elaborating such gradients by assembling particles from a library of functionalized microspheres. We propose a simple process to More >

  • Open Access

    ARTICLE

    Computational Investigation of Droplets Behaviour inside Passive Microfluidic Oscillator

    Tawfiq Chekifi1, *, Brahim Dennai2, Rachid Khelfaoui2

    FDMP-Fluid Dynamics & Materials Processing, Vol.13, No.3, pp. 173-187, 2017, DOI:10.3970/fdmp.2017.013.173

    Abstract Recently, modeling immiscible fluids such as oil and water have been a classical research topic. Droplet-based microfluidics presents a unique platform for mixing, reaction, separation, dispersion of drops and many other functions. In this paper, we suggest a numerical CFD study of microfluidic oscillator with two different lengths of feedback loop. In order to produce simultaneous droplets of gasoil on water, a typical geometry that includes double T-junction is connected to the fluidic oscillator. Droplets production is computed by volume-of-fluid method (VOF). Flow oscillations of droplets were triggered by the Coanda effect of jet flow. More >

  • Open Access

    ARTICLE

    Viscoelastic Drop Deformation in a Micro-Contraction

    Malcolm R. Davidson1, Dalton J.E. Harvie1

    FDMP-Fluid Dynamics & Materials Processing, Vol.7, No.3, pp. 317-328, 2011, DOI:10.3970/fdmp.2011.007.317

    Abstract A volume-of-fluid numerical method, adapted by the authors [Harvie, Cooper-White and Davidson (2008)] to simulate the flow of viscoelastic fluids, is used to predict deformation of a viscoelastic droplet carried by an immiscible Newtonian liquid through an axisymmetric microfluidic contraction-expansion. Values of the capillary number and elasticity number are chosen based on corresponding values for a rectangular contraction for which a reentrant cavity at the rear of the drop and subsequent encapsulation behaviour was observed experimentally by Harvie, Cooper-White and Davidson (2008). A reentrant cavity, similar to the observed one, is predicted; however, encapsulation is More >

  • Open Access

    ARTICLE

    Numerical Simulation of Fluid Induced Vibration of Graphenes at Micron Scales

    Y. Inoue1, R. Kobayashi1, S. Ogata1, T. Gotoh1

    CMES-Computer Modeling in Engineering & Sciences, Vol.63, No.2, pp. 137-162, 2010, DOI:10.3970/cmes.2010.063.137

    Abstract Vibration of a single graphene and a pair of graphenes at micro meter scale induced by air flow is numerically simulated and examined by using a hybrid computational method starting from a microscopic level of description for the graphene. In order to bridge a huge gap in spatial and time scales in their motions, the carbon atoms of the graphene are represented by a small number of coarse grained particles, the fluid motion is described by the lattice Boltzmann equation and the momentum exchange at the boundary is treated by the time averaged immersed boundary… More >

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