Tarek A ATIA
BIOCELL, Vol.43, No.4, pp. 253-262, 2019, DOI:10.32604/biocell.2019.08180
Abstract Recurring miscarriage (RM) is a frustrating reproductive complication with variable etiology. Numerous
genetic defects have been known to play a crucial role in the etiology of RM. Chromosomal abnormalities are
frequently detected, while other genetic defects cannot be diagnosed through routine research, such as cryptic
chromosomal anomalies, single nucleotide polymorphism, single-gene defect, and gene copy number variation.
Diagnostic laboratories have recently used variable advanced techniques to detect potential genetic abnormalities in
couples with RM and/or in products of conception. Here we aim to summarize the known genetic causes of RM, with
a focus on the new diagnostic techniques. Knowledge of… More >
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