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  • Open Access

    ARTICLE

    Improving Security-Sensitive Deep Learning Models through Adversarial Training and Hybrid Defense Mechanisms

    Xuezhi Wen1, Eric Danso2,*, Solomon Danso2

    Journal of Cyber Security, Vol.7, pp. 45-69, 2025, DOI:10.32604/jcs.2025.063606 - 08 May 2025

    Abstract Deep learning models have achieved remarkable success in healthcare, finance, and autonomous systems, yet their security vulnerabilities to adversarial attacks remain a critical challenge. This paper presents a novel dual-phase defense framework that combines progressive adversarial training with dynamic runtime protection to address evolving threats. Our approach introduces three key innovations: multi-stage adversarial training with TRADES (Tradeoff-inspired Adversarial Defense via Surrogate-loss minimization) loss that progressively scales perturbation strength, maintaining 85.10% clean accuracy on CIFAR-10 (Canadian Institute for Advanced Research 10-class dataset) while improving robustness; a hybrid runtime defense integrating feature manipulation, statistical anomaly detection, and… More >

  • Open Access

    VIEWPOINT

    The SS18-SSX fusion oncoprotein: Friend and foe in targeted therapy for synovial sarcoma

    GAVIN M. ANCHONDO, KYRA PARKER, ALEXIS BRUCE, ELIZABETH CORTEZ, LE SU*

    Oncology Research, Vol.33, No.5, pp. 1001-1005, 2025, DOI:10.32604/or.2025.060573 - 18 April 2025

    Abstract Synovial sarcoma is a high-grade soft tissue malignancy characterized by a unique fusion gene known as SS18-SSX. The SS18-SSX fusion protein acts as an oncogenic driver of synovial sarcoma, and it has thus been commonly accepted that disruption of SS18-SSX function represents a therapeutic means of treating synovial sarcoma, but emerging evidence suggests that upon depletion of SS18-SSX, an anti-apoptotic signal surprisingly arises to protect synovial sarcoma cell survival. In this article, we discuss the controversial roles of SS18-SSX’s transcriptional activity in synovial sarcoma biology and outline a synergistic strategy for overcoming the resistance of More > Graphic Abstract

    The SS18-SSX fusion oncoprotein: Friend and foe in targeted therapy for synovial sarcoma

  • Open Access

    REVIEW

    Research progress on cancer-associated fibroblasts in osteosarcoma

    LIWEN FENG1,2,#,*, YUTING CHEN3,#, WENYI JIN4

    Oncology Research, Vol.33, No.5, pp. 1091-1103, 2025, DOI:10.32604/or.2024.054207 - 18 April 2025

    Abstract Osteosarcoma (OS) is a prevalent primary bone malignancy with limited treatment options. Therefore, it is imperative to investigate and understand the mechanisms underlying OS pathogenesis. Cancer-associated fibroblasts (CAFs) are markedly abundant in tumor stromal cells and are essentially involved in the modulation of tumor occurrence and development. In recent years, CAFs have become a hotspot as researchers aim to elucidate CAF mechanisms that regulate tumor progression. However, most studies on CAFs are limited to a few common cancers, and their association with OS remains elusive. This review describes the role and current knowledge of CAFs More >

  • Open Access

    ARTICLE

    Wavelet Transform Convolution and Transformer-Based Learning Approach for Wind Power Prediction in Extreme Scenarios

    Jifeng Liang1, Qiang Wang2, Leibao Wang1, Ziwei Zhang3, Yonghui Sun3,*, Hongzhu Tao4, Xiaofei Li5

    CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.1, pp. 945-965, 2025, DOI:10.32604/cmes.2025.062315 - 11 April 2025

    Abstract Wind power generation is subjected to complex and variable meteorological conditions, resulting in intermittent and volatile power generation. Accurate wind power prediction plays a crucial role in enabling the power grid dispatching departments to rationally plan power transmission and energy storage operations. This enhances the efficiency of wind power integration into the grid. It allows grid operators to anticipate and mitigate the impact of wind power fluctuations, significantly improving the resilience of wind farms and the overall power grid. Furthermore, it assists wind farm operators in optimizing the management of power generation facilities and reducing… More > Graphic Abstract

    Wavelet Transform Convolution and Transformer-Based Learning Approach for Wind Power Prediction in Extreme Scenarios

  • Open Access

    ARTICLE

    Integrating Attention Mechanisms in YOLOv8 for Improved Fall Detection Performance

    Nizar Zaghden1, Emad Ibrahim2, Mukaram Safaldin2,*, Mahmoud Mejdoub3

    CMC-Computers, Materials & Continua, Vol.83, No.1, pp. 1117-1147, 2025, DOI:10.32604/cmc.2025.061948 - 26 March 2025

    Abstract The increasing elderly population has heightened the need for accurate and reliable fall detection systems, as falls can lead to severe health complications. Existing systems often suffer from high false positive and false negative rates due to insufficient training data and suboptimal detection techniques. This study introduces an advanced fall detection model integrating YOLOv8, Faster R-CNN, and Generative Adversarial Networks (GANs) to enhance accuracy and robustness. A modified YOLOv8 architecture serves as the core, utilizing spatial attention mechanisms to improve critical image regions’ detection. Faster R-CNN is employed for fine-grained human posture analysis, while GANs… More >

  • Open Access

    ARTICLE

    PKME-MLM: A Novel Multimodal Large Model for Sarcasm Detection

    Jian Luo1, Yaling Li1, Xueyu Li1, Xuliang Hu2,*

    CMC-Computers, Materials & Continua, Vol.83, No.1, pp. 877-896, 2025, DOI:10.32604/cmc.2025.061401 - 26 March 2025

    Abstract Sarcasm detection in Natural Language Processing (NLP) has become increasingly important, particularly with the rise of social media and non-textual emotional expressions, such as images. Existing methods often rely on separate image and text modalities, which may not fully utilize the information available from both sources. To address this limitation, we propose a novel multimodal large model, i.e., the PKME-MLM (Prior Knowledge and Multi-label Emotion analysis based Multimodal Large Model for sarcasm detection). The PKME-MLM aims to enhance sarcasm detection by integrating prior knowledge to extract useful textual information from images, which is then combined… More >

  • Open Access

    ARTICLE

    Enhancing Adversarial Example Transferability via Regularized Constrained Feature Layer

    Xiaoyin Yi1,2, Long Chen1,3,4,*, Jiacheng Huang1, Ning Yu1, Qian Huang5

    CMC-Computers, Materials & Continua, Vol.83, No.1, pp. 157-175, 2025, DOI:10.32604/cmc.2025.059863 - 26 March 2025

    Abstract Transfer-based Adversarial Attacks (TAAs) can deceive a victim model even without prior knowledge. This is achieved by leveraging the property of adversarial examples. That is, when generated from a surrogate model, they retain their features if applied to other models due to their good transferability. However, adversarial examples often exhibit overfitting, as they are tailored to exploit the particular architecture and feature representation of source models. Consequently, when attempting black-box transfer attacks on different target models, their effectiveness is decreased. To solve this problem, this study proposes an approach based on a Regularized Constrained Feature More >

  • Open Access

    ARTICLE

    YOLO-SIFD: YOLO with Sliced Inference and Fractal Dimension Analysis for Improved Fire and Smoke Detection

    Mariam Ishtiaq1,2, Jong-Un Won1,2,*

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 5343-5361, 2025, DOI:10.32604/cmc.2025.061466 - 06 March 2025

    Abstract Fire detection has held stringent importance in computer vision for over half a century. The development of early fire detection strategies is pivotal to the realization of safe and smart cities, inhabitable in the future. However, the development of optimal fire and smoke detection models is hindered by limitations like publicly available datasets, lack of diversity, and class imbalance. In this work, we explore the possible ways forward to overcome these challenges posed by available datasets. We study the impact of a class-balanced dataset to improve the fire detection capability of state-of-the-art (SOTA) vision-based models and proposeMore >

  • Open Access

    ARTICLE

    Hybrid Memory-Enhanced Autoencoder with Adversarial Training for Anomaly Detection in Virtual Power Plants

    Yuqiao Liu1, Chen Pan1, YeonJae Oh2,*, Chang Gyoon Lim1,*

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4593-4629, 2025, DOI:10.32604/cmc.2025.061196 - 06 March 2025

    Abstract Virtual Power Plants (VPPs) are integral to modern energy systems, providing stability and reliability in the face of the inherent complexities and fluctuations of solar power data. Traditional anomaly detection methodologies often need to adequately handle these fluctuations from solar radiation and ambient temperature variations. We introduce the Memory-Enhanced Autoencoder with Adversarial Training (MemAAE) model to overcome these limitations, designed explicitly for robust anomaly detection in VPP environments. The MemAAE model integrates three principal components: an LSTM-based autoencoder that effectively captures temporal dynamics to distinguish between normal and anomalous behaviors, an adversarial training module that… More >

  • Open Access

    ARTICLE

    Improving Robustness for Tag Recommendation via Self-Paced Adversarial Metric Learning

    Zhengshun Fei1,*, Jianxin Chen1, Gui Chen2, Xinjian Xiang1,*

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4237-4261, 2025, DOI:10.32604/cmc.2025.059262 - 06 March 2025

    Abstract Tag recommendation systems can significantly improve the accuracy of information retrieval by recommending relevant tag sets that align with user preferences and resource characteristics. However, metric learning methods often suffer from high sensitivity, leading to unstable recommendation results when facing adversarial samples generated through malicious user behavior. Adversarial training is considered to be an effective method for improving the robustness of tag recommendation systems and addressing adversarial samples. However, it still faces the challenge of overfitting. Although curriculum learning-based adversarial training somewhat mitigates this issue, challenges still exist, such as the lack of a quantitative… More >

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