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  • Open Access

    ARTICLE

    Profiles of Parent-Child Attachment and Peer Attachment among Adolescents and Associations with Internalizing Problems

    Chao Qu, Xiaoshan Jia, Haidong Zhu*

    International Journal of Mental Health Promotion, Vol.27, No.3, pp. 401-420, 2025, DOI:10.32604/ijmhp.2025.061059 - 31 March 2025

    Abstract Objectives: Attachment is a profound and enduring connection to the emotion children progressively form with their parents as they mature. It significantly impacts the social and psychological development of kids and teenagers. This study aimed to explore the latent profiles and longitudinal transition patterns of parent-child and peer attachments among adolescents. Methods: A cohort of 914 participants from China completed the measures with a twelve-month interval. There were 46.8% boys and 53.2% girls in this survey. Latent profile analysis (LPA) was adopted to explore the distinct profiles reflecting different parent-child and peer attachment response patterns… More >

  • Open Access

    ARTICLE

    Association between Mental Distress and Weight-Related Self-Stigma via Problematic Social Media and Smartphone Use among Malaysian University Students: An Application of the Interaction of Person-Affect-Cognition- Execution (I-PACE) Model

    Wan Ying Gan1,#,*, Wei-Leng Chin2,3,#, Shih-Wei Huang4,5, Serene En Hui Tung6, Ling Jun Lee1, Wai Chuen Poon7, Yan Li Siaw8, Kerry S. O’Brien9, Iqbal Pramukti10, Kamolthip Ruckwongpatr11, Jung-Sheng Chen12, Mark D. Griffiths13, Chung-Ying Lin10,11,14,15,*

    International Journal of Mental Health Promotion, Vol.27, No.3, pp. 319-331, 2025, DOI:10.32604/ijmhp.2025.060049 - 31 March 2025

    Abstract Background: Weight-related self-stigma (WRSS) is prevalent among individuals with different types of weight status and is associated with a range of negative health outcomes. Social support and coping models explain how individuals may use different coping methods to deal with their mental health needs. Psychological distress (e.g., depression and stress) could lead to overuse of social media and smartphones. When using social media or smartphones, individuals are likely to be exposed to negative comments regarding weight/shape/size posted on the social media. Consequently, individuals who experience problematic social media use (PSMU) or problematic smartphone use (PSPU)… More >

  • Open Access

    REVIEW

    Mitochondrial Oxidative Stress-Associated Mechanisms in the Development of Metabolic Dysfunction-Associated Steatotic Liver Disease

    Juan Yang1,2,#, Jiahui Zhang3,#, Le Zhang1,2,*, Zhenshan Yang4,*

    BIOCELL, Vol.49, No.3, pp. 399-417, 2025, DOI:10.32604/biocell.2025.059908 - 31 March 2025

    Abstract With the prevalence of obesity, metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most common chronic liver disease worldwide and can cause a series of serious complications. The pathogenesis of MASLD is complex, characterized by oxidative stress, impaired mitochondrial function and lipid metabolism, and cellular inflammation. Mitochondrial biology and function are central to the physiology of the liver. It has been suggested that mitochondrial oxidative stress plays a crucial role in MASLD progression. Excessive oxidative stress response is an important trigger for the occurrence and development of MASLD. In this review, we aim to More >

  • Open Access

    ARTICLE

    A Genetic Approach to Minimising Gate and Qubit Teleportations for Multi-Processor Quantum Circuit Distribution

    Oliver Crampton1,*, Panagiotis Promponas1,2, Richard Chen1, Paul Polakos1, Leandros Tassiulas2, Louis Samuel1

    Journal of Quantum Computing, Vol.7, pp. 1-15, 2025, DOI:10.32604/jqc.2025.061275 - 21 March 2025

    Abstract Distributed Quantum Computing (DQC) provides a means for scaling available quantum computation by interconnecting multiple quantum processor units (QPUs). A key challenge in this domain is efficiently allocating logical qubits from quantum circuits to the physical qubits within QPUs, a task known to be NP-hard. Traditional approaches, primarily focused on graph partitioning strategies, have sought to reduce the number of required Bell pairs for executing non-local CNOT operations, a form of gate teleportation. However, these methods have limitations in terms of efficiency and scalability. Addressing this, our work jointly considers gate and qubit teleportations introducing… More >

  • Open Access

    ARTICLE

    COPB2 promotes hepatocellular carcinoma progression through regulation of YAP1 nuclear translocation

    BIAO WU1,#, XIANLIN GUO2,#, ZHISHI WU1, LIANG CHEN1,*, SUQING ZHANG3,*

    Oncology Research, Vol.33, No.4, pp. 975-988, 2025, DOI:10.32604/or.2025.058085 - 19 March 2025

    Abstract Objectives: Although Yes-associated protein 1 (YAP1) is an important oncogene in hepatocellular carcinoma (HCC) progression, its nuclear localization prevents it from being considered a potential therapeutic target. Recently, studies have reported that coatomer protein complex subunit beta 2 (COPB2) also plays a critical role in HCC development; however its mechanism of action is unclear. This study aimed to investigate the role of COPB2 and YAP1 in the progression of HCC and to elucidate the underlying mechanisms. Methods: COPB2 and YAP1 expression in HCC tissues were first analyzed by database searches and immunohistochemistry. Nomogram and artificial… More >

  • Open Access

    ARTICLE

    Microglia and brain macrophages are differentially associated with tumor necrosis in glioblastoma: A link to tumor progression

    CHRISTINA LOH1, YUQI ZHENG1, ISLAM ALZOUBI2, KIMBERLEY L. ALEXANDER3,4, MAGGIE LEE4, WEI-DONG CAI2, YANG SONG5, KERRIE MCDONALD6, ANNA K. NOWAK7, RICHARD B. BANATI8,9, MANUEL B. GRAEBER1,4,10,*

    Oncology Research, Vol.33, No.4, pp. 937-950, 2025, DOI:10.32604/or.2024.056436 - 19 March 2025

    Abstract Background: Microglia and brain macrophages contribute significantly to the tumor microenvironment in highly malignant glioblastoma where they are considered important drivers of tumor progression. A better understanding of the role of the brain macrophages present in glioblastoma appears crucial for improving therapeutic outcomes, especially in the context of novel immunotherapeutic approaches. Methods: We investigated the regulation of two well-established markers for microglia and brain macrophages, IBA1 and CD163, in relation to glioblastoma tumor necrosis using immunohistochemistry and modality fusion heatmaps of whole slide images obtained from adjacent tissue sections. Results: IBA1 and CD163 showed remarkable differences… More >

  • Open Access

    ARTICLE

    An Enhanced Task Migration Technique Based on Convolutional Neural Network in Machine Learning Framework

    Hamayun Khan1,*, Muhammad Atif Imtiaz2, Hira Siddique3, Muhammad Tausif Afzal Rana4, Arshad Ali5, Muhammad Zeeshan Baig6, Saif ur Rehman7, Yazed Alsaawy5

    Computer Systems Science and Engineering, Vol.49, pp. 317-331, 2025, DOI:10.32604/csse.2025.061118 - 19 March 2025

    Abstract The migration of tasks aided by machine learning (ML) predictions IN (DPM) is a system-level design technique that is used to reduce energy by enhancing the overall performance of the processor. In this paper, we address the issue of system-level higher task dissipation during the execution of parallel workloads with common deadlines by introducing a machine learning-based framework that includes task migration using energy-efficient earliest deadline first scheduling (EA-EDF). ML-based EA-EDF enhances the overall throughput and optimizes the energy to avoid delay and performance degradation in a multiprocessor system. The proposed system model allocates processors… More >

  • Open Access

    ARTICLE

    Impaired Magnetic Resonance Myocardial Strain in Unoperated Ebstein’s Anomaly Is Associated with Reduced Exercise Capacity

    Ahmed M. Dardeer1,2,3,#, Victoria M. Stoll1,2,#, Boyang Liu1,2, William E. Moody1,2, Colin D. Chue1, Paul Clift1,2, Roman Wesolowski4, Lucy E. Hudsmith1, Richard P. Steeds1,2,*

    Congenital Heart Disease, Vol.20, No.1, pp. 27-39, 2025, DOI:10.32604/chd.2025.059729 - 18 March 2025

    Abstract Background: Patients with unrepaired Ebstein’s anomaly experience exercise intolerance, heart failure and premature mortality. Volumetric assessment of right ventricular function is difficult due to the complex anatomy of the right ventricle and tricuspid valve. Myocardial deformation indices are an early marker in other cardiac pathologies of ventricular dysfunction. Objectives: 1. Assess myocardial deformation in unrepaired Ebstein’s compared to healthy controls. 2. Investigate the relationships between myocardial deformation and exercise capacity. Methods: Myocardial deformation parameters (strain) were calculated using feature tracking from standard cardiac magnetic resonance cine images. Cardiopulmonary exercise results were included where available. Results: 36 patients… More >

  • Open Access

    ARTICLE

    Cross-Modal Simplex Center Learning for Speech-Face Association

    Qiming Ma, Fanliang Bu*, Rong Wang, Lingbin Bu, Yifan Wang, Zhiyuan Li

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 5169-5184, 2025, DOI:10.32604/cmc.2025.061187 - 06 March 2025

    Abstract Speech-face association aims to achieve identity matching between facial images and voice segments by aligning cross-modal features. Existing research primarily focuses on learning shared-space representations and computing one-to-one similarities between cross-modal sample pairs to establish their correlation. However, these approaches do not fully account for intra-class variations between the modalities or the many-to-many relationships among cross-modal samples, which are crucial for robust association modeling. To address these challenges, we propose a novel framework that leverages global information to align voice and face embeddings while effectively correlating identity information embedded in both modalities. First, we jointly… More >

  • Open Access

    ARTICLE

    A Barrier-Based Machine Learning Approach for Intrusion Detection in Wireless Sensor Networks

    Haydar Abdulameer Marhoon1,2,*, Rafid Sagban3,4, Atheer Y. Oudah1,5, Saadaldeen Rashid Ahmed6,7

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4181-4218, 2025, DOI:10.32604/cmc.2025.058822 - 06 March 2025

    Abstract In order to address the critical security challenges inherent to Wireless Sensor Networks (WSNs), this paper presents a groundbreaking barrier-based machine learning technique. Vital applications like military operations, healthcare monitoring, and environmental surveillance increasingly deploy WSNs, recognizing the critical importance of effective intrusion detection in protecting sensitive data and maintaining operational integrity. The proposed method innovatively partitions the network into logical segments or virtual barriers, allowing for targeted monitoring and data collection that aligns with specific traffic patterns. This approach not only improves the diversit. There are more types of data in the training set,… More >

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