Zhifang Liao¹, Fangying Fu¹, Yiqi Zhao¹, Sui Tan^2,3,*, Zhiwu Yu^2,3, Yan Zhang⁴

Computer Systems Science and Engineering, Vol.47, No.1, pp. 431-452, 2023, DOI:10.32604/csse.2023.038087 - 26 May 2023

Abstract With the rapid development of Open-Source (OS), more and more software projects are maintained and developed in the form of OS. These Open-Source projects depend on and influence each other, gradually forming a huge OS project network, namely an Open-Source Software ECOsystem (OSSECO). Unfortunately, not all OS projects in the open-source ecosystem can be healthy and stable in the long term, and more projects will go from active to inactive and gradually die. In a tightly connected ecosystem, the death of one project can potentially cause the collapse of the entire ecosystem network. How can… More >

OZAN CEM GULER^1,*, EZGI OYMAK², GOZDE YAZICI³, OZLEM OZKAYA AKAGUNDUZ⁴, OGUZ CETINAYAK⁵, PETEK ERPOLAT⁶, ATIL AKSOY⁷, MURSEL DUZOVA⁸, BERNA AKKUS YILDIRIM⁹, MERAL KURT¹⁰, EMINE CANYILMAZ¹¹, GULER YAVAS¹², SERAP AKYUREK¹³, DIDEM COLPAN OKSUZ¹⁴, ESRA KAYTAN SAGLAM¹⁵, OMUR KARAKOYUN CELIK¹⁶, ENIS OZYAR¹⁷, MUSTAFA CENGIZ³, CEM ONAL^1,2,12

Oncology Research, Vol.31, No.3, pp. 299-306, 2023, DOI:10.32604/or.2023.028840 - 22 May 2023

Abstract The aim of this study was to examine the prognostic factors and treatment outcomes of cervical esophageal carcinoma (CEC) patients who underwent definitive chemoradiotherapy (CRT). The clinical data of 175 biopsy-confirmed CEC patients treated with definitive CRT between April 2005 and September 2021 were retrospectively analyzed. The prognostic factors predicting overall survival (OS), progression-free survival (PFS), and local recurrence-free survival (LRFS) were assessed in uni- and multivariable analyses. The median age of the entire cohort was 56 years (range: 26–87 years). All patients received definitive radiotherapy with a median total dose of 60 Gy, and… More >

Salah Alzghoul^1,*, Othman Smadi¹, Ali Al Bataineh², Mamon Hatmal³, Ahmad Alamm⁴

Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 455-470, 2023, DOI:10.32604/iasc.2023.038338 - 29 April 2023

Abstract Currently, the decision of aortic valve replacement surgery time for asymptomatic patients with moderate-to-severe aortic stenosis (AS) is made by healthcare professionals based on the patient’s clinical biometric records. A delay in surgical aortic valve replacement (SAVR) can potentially affect patients’ quality of life. By using ML algorithms, this study aims to predict the optimal SAVR timing and determine the enhancement in moderate-to-severe AS patient survival following surgery. This study represents a novel approach that has the potential to improve decision-making and, ultimately, improve patient outcomes. We analyze data from 176 patients with moderate-to-severe aortic… More >

Alain J. Poncelet^1,*, Maureen Peers de Nieuwburgh², Stéphane Moniotte², Geoffroy de Beco¹, Karlien Carbonez², Jean E. Rubay¹, Thierry Detaille³, Laurent Houtekie³, Mona Momeni⁴

Congenital Heart Disease, Vol.18, No.2, pp. 151-168, 2023, DOI:10.32604/chd.2023.022636 - 15 March 2023

Abstract Background: Most outcome studies in congenital cardiac surgery for “low weight” neonates include patients undergoing surgery without cardiopulmonary bypass (CPB). The primary objective of our study was to identify risk factors for in-hospital mortality in neonates weighing less than 3 Kg and undergoing surgery with CPB. In addition, we compared the effect of early surgery with CPB (before 37W-gestational age (GA)) for congenital heart disease to delayed surgery until a corrected GA of 37 weeks in an attempt to promote weight gain. Methods: Retrospective single-center study including all patients operated between 1997 and 2017. Uni- and… More >

JULIANA A. PORTES¹, ROSSIANE C. VOMMARO¹, LUCIO AYRES CALDAS², ERICA S. MARTINS-DUARTE^3,*

BIOCELL, Vol.47, No.4, pp. 929-950, 2023, DOI:10.32604/biocell.2023.026629 - 08 March 2023

Abstract Toxoplasma gondii is a protozoan of worldwide distribution and the agent of toxoplasmosis. It is estimated that 30%–50% of the world population could be infected with this parasite. Although the infection in immunocompetent individuals is mostly asymptomatic, the disease in immunosuppressed and pregnant is a risk condition. As a member of the phylum Apicomplexa, T. gondii has an obligatory intracellular lifestyle; therefore, invading a host cell and establishing it inside a parasitophorous vacuole (PV) are mandatories for the survival of this parasite. The construction of a perfect intracellular niche for T. gondii requires the secretion of an arsenal More >

Nagaraju Jajam, Nagendra Panini Challa^*

CMC-Computers, Materials & Continua, Vol.75, No.1, pp. 977-997, 2023, DOI:10.32604/cmc.2023.036098 - 06 February 2023

Abstract In the insurance sector, a massive volume of data is being generated on a daily basis due to a vast client base. Decision makers and business analysts emphasized that attaining new customers is costlier than retaining existing ones. The success of retention initiatives is determined not only by the accuracy of forecasting churners but also by the timing of the forecast. Previous works on churn forecast presented models for anticipating churn quarterly or monthly with an emphasis on customers’ static behavior. This paper’s objective is to calculate daily churn based on dynamic variations in client… More >

WENLI ZENG¹, FENG LING², KAINUO DANG³, QINGJIA CHI^3,*

BIOCELL, Vol.47, No.3, pp. 581-592, 2023, DOI:10.32604/biocell.2023.025957 - 03 January 2023

Abstract Hepatocellular carcinoma (HCC) is associated with poor prognosis and fluctuations in immune status. Although studies have found that secreted phosphoprotein 1 (SPP1) is involved in HCC progression, its independent prognostic value and immune-mediated role remain unclear. Using The Cancer Genome Atlas and Gene Expression Omnibus data, we found that low expression of SPP1 is significantly associated with improved survival of HCC patients and that SPP1 expression is correlated with clinical characteristics. Univariate and multivariate Cox regression confirmed that SPP1 is an independent prognostic factor of HCC. Subsequently, we found that T cell CD4 memory-activated monocytes,… More >

Hassen Sallay^*

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 429-444, 2023, DOI:10.32604/iasc.2023.030791 - 29 September 2022

Abstract Security breaches can seriously harm the Internet of Things (IoT) and Industrial IoT (IIoT) environments. The damage can exceed financial and material losses to threaten human lives. Overcoming these security risks is challenging given IoT ubiquity, complexity, and restricted resources. Security intrusion management is a cornerstone in fortifying the defensive security process. This paper presents an integrated multilayered framework facilitating the orchestration of the security intrusion management process and developing security decision support systems. The proposed framework incorporates four layers with four dedicated processing phases. This paper focuses mainly on the analytical layer. We present… More >

LIPING GONG¹, MING JIA^2,*

BIOCELL, Vol.47, No.1, pp. 109-123, 2023, DOI:10.32604/biocell.2023.024620 - 26 September 2022

Abstract ATP binding cassette subfamily C member 8 (ABCC8) encodes a protein regulating the ATP-sensitive potassium channel. Whether the level of ABCC8 mRNA in lower grade glioma (LGG) correlates with immune cell infiltration and patient outcomes has not been evaluated until now. Comparisons of ABCC8 expression between different tumors and normal tissues were evaluated by exploring publicly available datasets. The association between ABCC8 and tumor immune cell infiltration, diverse gene mutation characteristics, tumor mutation burden (TMB), and survival in LGG was also investigated in several independent datasets. Pathway enrichment analysis was conducted to search for ABCC8-associated… More >

Alhanouf Alburaikan¹, Hamiden Abd El-Wahed Khalifa^1,2, Pavan Kumar^3,*, Seyedali Mirjalili^4,6, Ibrahim Mekawy⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.134, No.3, pp. 1943-1956, 2023, DOI:10.32604/cmes.2022.021815 - 20 September 2022

Abstract In this article, mathematical modeling for the evaluation of reliability is studied using two methods. One of the methods, is developed based on possibility theory. The performance of the reliability of the system is of prime concern. In view of this, the outcomes for the failure are required to evaluate with utmost care. In possibility theory, the reliability information data determined from decision-making experts are subjective. The same method is also related to the survival possibilities as against the survival probabilities. The other method is the one that is developed using the concept of approximation More >