S. Kannan^1,*, S. Anusuya²

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3835-3851, 2023, DOI:10.32604/cmc.2023.042465

Abstract Gliomas, the most prevalent primary brain tumors, require accurate segmentation for diagnosis and risk assessment. In this paper, we develop a novel deep learning-based method, the Dynamic Hierarchical Attention for Improved Segmentation and Survival Prognosis (DHA-ISSP) model. The DHA-ISSP model combines a three-band 3D convolutional neural network (CNN) U-Net architecture with dynamic hierarchical attention mechanisms, enabling precise tumor segmentation and survival prediction. The DHA-ISSP model captures fine-grained details and contextual information by leveraging attention mechanisms at multiple levels, enhancing segmentation accuracy. By achieving remarkable results, our approach surpasses 369 competing teams in the 2020 Multimodal Brain Tumor Segmentation Challenge. With… More >

Zhifang Liao¹, Fangying Fu¹, Yiqi Zhao¹, Sui Tan^2,3,*, Zhiwu Yu^2,3, Yan Zhang⁴

Computer Systems Science and Engineering, Vol.47, No.1, pp. 431-452, 2023, DOI:10.32604/csse.2023.038087

Abstract With the rapid development of Open-Source (OS), more and more software projects are maintained and developed in the form of OS. These Open-Source projects depend on and influence each other, gradually forming a huge OS project network, namely an Open-Source Software ECOsystem (OSSECO). Unfortunately, not all OS projects in the open-source ecosystem can be healthy and stable in the long term, and more projects will go from active to inactive and gradually die. In a tightly connected ecosystem, the death of one project can potentially cause the collapse of the entire ecosystem network. How can we effectively prevent such situations… More >

WENLI ZENG¹, FENG LING², KAINUO DANG³, QINGJIA CHI^3,*

BIOCELL, Vol.47, No.3, pp. 581-592, 2023, DOI:10.32604/biocell.2023.025957

Abstract Hepatocellular carcinoma (HCC) is associated with poor prognosis and fluctuations in immune status. Although studies have found that secreted phosphoprotein 1 (SPP1) is involved in HCC progression, its independent prognostic value and immune-mediated role remain unclear. Using The Cancer Genome Atlas and Gene Expression Omnibus data, we found that low expression of SPP1 is significantly associated with improved survival of HCC patients and that SPP1 expression is correlated with clinical characteristics. Univariate and multivariate Cox regression confirmed that SPP1 is an independent prognostic factor of HCC. Subsequently, we found that T cell CD4 memory-activated monocytes, M0 macrophages, and resting mast… More >