Sebastian Udholm, Christian Rex, Filip Eckerström, Mine Onat, Camilla Nyboe, Vibeke E. Hjortdal
Congenital Heart Disease, Vol.14, No.3, pp. 372-379, 2019, DOI:10.1111/chd.12740
Abstract Objective: Adult patients with small, unrepaired atrial septal defects have an in‐
creased risk of pneumonia, atrial fibrillation, and stroke. Furthermore, they have
higher late mortality than the background population. The functional capacity is un‐
known in these patients. Therefore, our objective was to determine exercise capacity
in adult patients diagnosed with an unrepaired atrial septal defect compared to
healthy controls.
Design: A cross‐sectional study.
Patients: Adult patients with small, unrepaired atrial septal defects, aged 18‐65, di‐
agnosed between 1953 and 2011.
Interventions: Cardiopulmonary exercise test was performed using an incremental
bicycle test and gas exchange was measured using breath‐by‐breath… More >
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