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    ARTICLE

    Renal dysfunction is associated with higher central venous pressures in patients with Fontan circulation

    Christopher R. Broda1, Hamsini Sriraman2, Devanshi Wadhwa2, YunFei Wang1, Hari Tunuguntla1, Ayse Akcan-Arikan3,4, Peter R. Ermis1, Jack F. Price1

    Congenital Heart Disease, Vol.13, No.4, pp. 602-607, 2018, DOI:10.1111/chd.12617

    Abstract Purpose: Elevated central venous pressure (CVP) has deleterious effects on several organ systems in patients with Fontan circulation. However, the relationship between CVP and estimated glomerular filtration rate (eGFR) has not been assessed in patients with Fontan circulation.
    Methods: Patients with Fontan circulation whose hemodynamics were assessed by catheterization between 1987 and 2015 and had a serum creatinine measured within 72 hours prior to the procedure were included for analysis. Patients with primary kidney disease were excluded. Renal function was calculated by “bedside Schwartz” equation in children (< 18 years) and Modification of Diet in Renal Disease equation in adults.… More >

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