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  • Open Access

    ARTICLE

    A Coordinated Multi-Loop Control Strategy for Fault Ride-Through in Grid-Forming Converters

    Zhuang Liu#, Mingwei Ren, Kai Shi*, Peifeng Xu

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.069480 - 27 December 2025

    Abstract Grid-Forming (GFM) converters are prone to fault-induced overcurrent and power angle instability during grid fault-induced voltage sags. To address this, this paper develops a multi-loop coordinated fault ride-through (FRT) control strategy based on a power outer loop and voltage-current inner loops, aiming to enhance the stability and current-limiting capability of GFM converters during grid fault conditions. During voltage sags, the GFM converter’s voltage source behavior is maintained by dynamically adjusting the reactive power reference to provide voltage support, thereby effectively suppressing the steady-state component of the fault current. To address the active power imbalance induced… More >

  • Open Access

    REVIEW

    Transforming Healthcare with State-of-the-Art Medical-LLMs: A Comprehensive Evaluation of Current Advances Using Benchmarking Framework

    Himadri Nath Saha1, Dipanwita Chakraborty Bhattacharya2,*, Sancharita Dutta3, Arnab Bera3, Srutorshi Basuray4, Satyasaran Changdar5, Saptarshi Banerjee6, Jon Turdiev7

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-56, 2026, DOI:10.32604/cmc.2025.070507 - 09 December 2025

    Abstract The emergence of Medical Large Language Models has significantly transformed healthcare. Medical Large Language Models (Med-LLMs) serve as transformative tools that enhance clinical practice through applications in decision support, documentation, and diagnostics. This evaluation examines the performance of leading Med-LLMs, including GPT-4Med, Med-PaLM, MEDITRON, PubMedGPT, and MedAlpaca, across diverse medical datasets. It provides graphical comparisons of their effectiveness in distinct healthcare domains. The study introduces a domain-specific categorization system that aligns these models with optimal applications in clinical decision-making, documentation, drug discovery, research, patient interaction, and public health. The paper addresses deployment challenges of Medical-LLMs, More >

  • Open Access

    ARTICLE

    Taraxasterol Ameliorates Pulmonary Fibrosis by Regulating PPP2R1B Expression

    Huiping Qiu1, Shaofang Huang2,*, Xin Xiong1, Li Zhang1

    BIOCELL, Vol.49, No.12, pp. 2415-2432, 2025, DOI:10.32604/biocell.2025.070402 - 24 December 2025

    Abstract Background: Pulmonary fibrosis is an irreversible lung disorder that currently has a limited number of effective therapeutic strategies. Taraxasterol (TAR), a bioactive triterpenoid isolated from plants used in traditional Chinese medicine (TCM), possesses anti-inflammatory and antioxidant activities. However, its precise role in pulmonary fibrosis remains incompletely defined. This study aimed to elucidate whether TAR alleviates pulmonary fibrosis by modulating Protein Phosphatase 2 Scaffold Subunit Abeta (PPP2R1B) expression. Methods: A bleomycin-induced murine model of pulmonary fibrosis and a transforming growth factor-β1 (TGF-β1) stimulated mouse lung fibroblast cell line (MLg) were established. To evaluate the effects of… More >

  • Open Access

    REVIEW

    Transforming Sawdust Waste into Renewable Energy Resources: A Comprehensive Review on Sustainable Bio-Oil and Biochar Production via Thermochemical Processes

    Hauwau Kaoje1,2, Adekunle Adeleke2,3,*, Esther Anosike-Francis2,3, Seun Jesuloluwa2,3, Temitayo Ogedengbe2,3, Hauwa Rasheed2, Jude Okolie4

    Journal of Renewable Materials, Vol.13, No.12, pp. 2375-2430, 2025, DOI:10.32604/jrm.2025.02025-0109 - 23 December 2025

    Abstract The increasing need for sustainable energy and the environmental impacts of reliance on fossil fuels have sparked greater interest in biomass as a renewable energy source. This review provides an in-depth assessment of bio-oil and biochar generation through the pyrolysis of sawdust, a significant variety of lignocellulosic biomass. The paper investigates different thermochemical conversion methods, including fast, slow, catalytic, flash, and co-pyrolysis, while emphasizing their operational parameters, reactor designs, and effects on product yields. The influence of temperature, heating rate, and catalysts on enhancing the quality and quantity of bio-oil and biochar is thoroughly analyzed. More > Graphic Abstract

    Transforming Sawdust Waste into Renewable Energy Resources: A Comprehensive Review on Sustainable Bio-Oil and Biochar Production via Thermochemical Processes

  • Open Access

    REVIEW

    Research Advances in the Application of Non-Nickel-Based Perovskite Materials for Biogas Reforming

    Hao Tan1,2, Zeai Huang1,2,*, Runxian Gong2, Junming Mei2, Kejie Wu2, Tianyu Yan2, Daoquan Zhu2, Zhibin Zhang2, Ruiyang Zhang1,2

    Energy Engineering, Vol.122, No.11, pp. 4331-4347, 2025, DOI:10.32604/ee.2025.070226 - 27 October 2025

    Abstract Under the driving goal of carbon neutrality, biogas reforming technology has garnered significant attention due to its ability to convert greenhouse gases (CH4/CO2) into syngas (H2/CO). Conventional nickel-based catalysts suffer from issues such as carbon deposition, sintering and sulfur poisoning. Non-nickel-based perovskite materials, with their tunable crystal structure, dynamic oxygen vacancy characteristics, and excellent anti-coking/anti-sulfur performance, have emerged as a promising alternative. This review systematically summarizes the design for non-nickel-based perovskite materials, including optimizing lattice oxygen migration ability and active site stability by A/B site doping, defect engineering and heterojunction construction. The enhancing the conversion rate… More > Graphic Abstract

    Research Advances in the Application of Non-Nickel-Based Perovskite Materials for Biogas Reforming

  • Open Access

    ARTICLE

    Optimization Configuration Method for Grid-Side Grid-Forming Energy Storage System Based on Genetic Algorithm

    Yuqian Qi*, Yanbo Che, Liangliang Liu, Jiayu Ni, Shangyuan Zhang

    Energy Engineering, Vol.122, No.10, pp. 3999-4017, 2025, DOI:10.32604/ee.2025.068054 - 30 September 2025

    Abstract The process of including renewable energy sources in power networks is moving quickly, so the need for innovative configuration solutions for grid-side ESS has grown. Among the new methods presented in this paper is GA-OCESE, which stands for Genetic Algorithm-based Optimization Configuration for Energy Storage in Electric Networks. This is one of the methods suggested in this study, which aims to enhance the sizing, positioning, and operational characteristics of structured ESS under dynamic grid conditions. Particularly, the aim is to maximize efficiency. A multiobjective genetic algorithm, the GA-OCESE framework, considers all these factors simultaneously. Besides… More >

  • Open Access

    ARTICLE

    Calculation of Commutation Failure Overvoltage in High-Voltage Direct Current Transmission Terminal Systems with Grid-Forming Renewable Energy Sources

    Weibing Xu1, Bo Yao2,*, Xiangjun Quan3, Xunyou Zhang1, Ning Zou2, Shuo Liu2, Jia Wang4, Jiansuo Zhang4

    Energy Engineering, Vol.122, No.10, pp. 4225-4243, 2025, DOI:10.32604/ee.2025.066738 - 30 September 2025

    Abstract The integration of large-scale new energy and high-capacity DC transmission leads to a reduction in system inertia. Grid-forming renewable energy sources (GF-RES) has a significant improvement effect on system inertia. Commutation failure faults may cause a short-term reactive power surplus at the sending end and trigger transient overvoltage, threatening the safe and stable operation of the power grid. However, there is a lack of research on the calculation method of transient overvoltage caused by commutation failure in high-voltage DC transmission systems with grid-forming renewable energy sources integration. Based on the existing equivalent model of high-voltage… More >

  • Open Access

    ARTICLE

    3-Hydroxysterol Δ24-Reductase Promotes Ovarian Cancer Progression by Activating the TGF-1/Smad2/3 Signaling Pathway

    Wenjing Liao1,#, Liaodi Wang2,#, Zhen Huang1, Ziyu Zou1, Yimin Liu1, Haoyue Liu1, Zhaoning Duan1, Liangdan Tang1,*

    Oncology Research, Vol.33, No.10, pp. 3041-3064, 2025, DOI:10.32604/or.2025.065451 - 26 September 2025

    Abstract Objectives: Ovarian cancer (OC) is a highly heterogeneous disease characterized by high metastatic potential and frequent recurrence. 3β-hydroxysterol Δ24-reductase (DHCR24) is closely associated with the progression of various malignant tumors, but its role in OC remains unexplored. This study is the first to systematically investigate the function of DHCR24 in OC and elucidate its mechanism in promoting OC progression, providing novel theoretical insights for targeted therapy. Methods: The expression of DHCR24 was evaluated in tissues using bioinformatics and clinical data; the impact of DHCR24 on the malignant behavior of OC was assessed through in vivo and inMore >

  • Open Access

    REVIEW

    Transforming the Leather Industry: A Comprehensive Review on Leather Alternatives

    Alehegn Atalay Birlie*

    Journal of Renewable Materials, Vol.13, No.9, pp. 1783-1802, 2025, DOI:10.32604/jrm.2025.02025-0039 - 22 September 2025

    Abstract This study explores vegan leather, an eco-friendly substitute for conventional animal-derived leather. Using materials like polyurethane, pineapple leaves, cork, and recycled plastics, vegan leather aims to transform the fashion industry and consumer products while addressing environmental concerns. Despite its advantages, challenges related to availability and durability persist. The booming market for vegan leather is expected to reach billions of dollars, reflecting a broader societal shift towards sustainable and cruelty-free alternatives. The review traces the historical development of vegan leather from its origins in Germany to modern innovations like Mylo and Piñatex. By comparing these materials More >

  • Open Access

    ARTICLE

    CYB5D2 inhibits the malignant progression of hepatocellular carcinoma by inhibiting TGF-β expression and epithelial-mesenchymal transition

    DONG JIANG1, ZHI QI3, ZHIYING XU2,*, YIRAN LI1,*

    Oncology Research, Vol.33, No.3, pp. 709-722, 2025, DOI:10.32604/or.2024.050125 - 28 February 2025

    Abstract Background: Hepatocellular carcinoma (HCC) is a prevalent liver malignancy. This study examined the roles of transforming growth factor beta (TGF-β) and cytochrome b5 domain containing 2 (CYB5D2) in HCC etiology and their prognostic biomarker potential. Methods: Key modules and prognostic genes were identified by analyzing the GSE101685 dataset by weighted gene co-expression network analysis (WGCNA) and Least absolute shrinkage and selection operator (LASSO) Cox regression. The expression levels of CYB5D2 and TGF-β in HCC cell lines were quantified using Quantitative reverse transcription polymerase chain reaction (qRT-PCR) and Western blotting (WB) assays. Effects of CYB5D2 overexpression on cell proliferation,… More >

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